Niemann-Pick C2 Protein Expression Regulates Lithogenic Diet-Induced Gallstone Formation and Dietary Cholesterol Metabolism in Mice

Niemann-Pick C2 protein (NPC2) is a lysosomal soluble protein that is highly expressed in the liver; it binds to cholesterol and is involved in intracellular cholesterol trafficking, allowing the exit of lysosomal cholesterol obtained via the lipoprotein

Detalles Bibliográficos
Autores: Balboa, E., Morales, G., Aylwin, P., Carrasco, G., Amigo, L., Castro, J., Rigotti, A., Zanlungo, S.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/238428
Acceso en línea:https://hdl.handle.net/10533/238428
Access Level:acceso abierto
Descripción
Sumario:Niemann-Pick C2 protein (NPC2) is a lysosomal soluble protein that is highly expressed in the liver; it binds to cholesterol and is involved in intracellular cholesterol trafficking, allowing the exit of lysosomal cholesterol obtained via the lipoprotein