Antifungal and wound healing potential of calendula officinalis for dental use: an in vitro study
Aim: To demonstrate the antifungal and healing properties of Calendula officinalis. Methods: We included four assays: inhibition halo, germicidal test, cytotoxicity test, and scratch test. Results: The extract at 100% and 50% concentrations was effective, and both presentations (Calendula officinali...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | Brasil |
| Institución: | Universidade Estadual de Campinas (UNICAMP) |
| Repositorio: | Brazilian journal of oral sciences (Online) |
| Idioma: | inglés |
| OAI Identifier: | oai:ojs.periodicos.sbu.unicamp.br:article/8675546 |
| Acceso en línea: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8675546 |
| Access Level: | acceso abierto |
| Palabra clave: | Antifungal agents Calendula Dentistry Phytotherapy Wound healing |
| Sumario: | Aim: To demonstrate the antifungal and healing properties of Calendula officinalis. Methods: We included four assays: inhibition halo, germicidal test, cytotoxicity test, and scratch test. Results: The extract at 100% and 50% concentrations was effective, and both presentations (Calendula officinalis extract and Calendula officinalis infusion) exhibited no cytotoxic effects. Furthermore, the infusion demonstrated a high healing effect without affecting the morphology of the cell monolayer and promoted fibroblastic proliferation. The extract did not show the expected healing results. Conclusions: Calendula officinalis holds considerable potential for further research across various biological processes, highlighting its promise as a subject for continued investigation. |
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