Tuberculosis in childhood and adolescence: prevalence and factors associated with treatment abandonment

Tuberculosis (TB) is an infectious disease that remains a serious public health problem worldwide. In the pediatric population, the knowledge about the factors that lead to the abandonment of TB treatment is limited, especially in regions with a high prevalence of the disease. This study aimed to id...

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Detalles Bibliográficos
Autores: Pereira da Soledade, Mariana, Miyuki Yamauti, Sueli, Simões Aguiar, Andressa, Sucupira, Carolina, Teresinha Lonardoni Crozatti, Márcia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Brasil
Institución:Fundação Oswaldo Cruz (FIOCRUZ)
Repositorio:Cadernos de Saúde Pública
Idioma:portugués
OAI Identifier:oai:ojs.teste-cadernos.ensp.fiocruz.br:article/8697
Acceso en línea:https://cadernos.ensp.fiocruz.br/ojs/index.php/csp/article/view/8697
Access Level:acceso abierto
Palabra clave:Tuberculose; Pediatria; Pacientes Desistentes do Tratamento; Fatores de Risco
Tuberculosis; Pediatría; Pacientes Desistentes del Tratamiento; Factores de Riesgo
Tuberculosis; Pediatrics; Patient Dropouts; Risk Factors
Descripción
Sumario:Tuberculosis (TB) is an infectious disease that remains a serious public health problem worldwide. In the pediatric population, the knowledge about the factors that lead to the abandonment of TB treatment is limited, especially in regions with a high prevalence of the disease. This study aimed to identify the prevalence and risk factors associated with TB treatment abandonment in children and adolescents. A cross-sectional study was carried out using data obtained from TB notifications from the São Paulo State Tuberculosis Patient Control System, Brazil, for individuals aged between 0 and 18 years, from January 2009 to December 2019. The crude and adjusted prevalence ratios were estimated with a 95% confidence interval, using the Poisson regression model to identify associations between the outcome of treatment abandonment and the sociodemographic, clinical-epidemiological, diagnostic and therapeutic factors of TB cases with complete information. Of the 12,256 cases analyzed, 941 individuals abandoned treatment. The highest prevalence rate of treatment abandonment occurs among Black or brown adolescents, those over 11 years of age and those deprived of their liberty. Other characteristics associated with treatment abandonment include: being a person living with HIV/AIDS, having a history of previous TB treatment, using illicit substances and using a self-administered TB treatment regimen. Knowing the profile of the patient most likely to abandon TB treatment makes it possible to devise more effective strategies focused on adherence to drug treatment.