Diagnóstico laboratorial do carcinoma medular de tiróide: calcitonina basal e testes de estímulo

Calcitonin is a hormone secreted by the parafollicular thyroid cells. Diagnosis of medullary thyroid carcinoma (MTC) should be considered when high basal calcitonin levels or high calcitonin levels after specific provocative test are found. In this context, calcitonin is considered a relevant tumor...

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Detalles Bibliográficos
Autores: Hauache, Omar M. [UNIFESP], Vieira, José Gilberto H. [UNIFESP], Maciel, Rui Monteiro de Barros [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/1862
Acceso en línea:http://dx.doi.org/10.1590/S0004-27302003000500005
http://repositorio.unifesp.br/handle/11600/1862
Access Level:acceso abierto
Palabra clave:Calcitonin
Medullary thyroid carcinoma
Provocative tests
Calcitonina
Carcinoma medular de tiróide
Testes de estímulo
Descripción
Sumario:Calcitonin is a hormone secreted by the parafollicular thyroid cells. Diagnosis of medullary thyroid carcinoma (MTC) should be considered when high basal calcitonin levels or high calcitonin levels after specific provocative test are found. In this context, calcitonin is considered a relevant tumor marker for diagnosis and follow-up of MTC. In this manuscript, we review some issues related to the usefulness of measuring basal calcitonin in patients with thyroid nodules. The current available provocative tests for calcitonin are discussed. Finally, we comment on some aspects related to the assays for calcitonin measurement.