Oral Films Printed with Green Propolis Ethanolic Extract

Remedio, Leandro Neodini; Garcia, Vitor Augusto dos Santos [UNESP]; Rochetti, Arina Lazaro; Berretta, Andresa Aparecida; Ferreira, Julieta Adriana; Fukumasu, Heidge; Vanin, Fernanda Maria; Yoshida, Cristiana Maria Pedroso; de Carvalho, Rosemary Aparecida

Oral Films Printed with Green Propolis Ethanolic Extract

Oral film (OF) research has intensified due to the effortless administration and advantages related to absorption in systemic circulation. Chitosan is one of the polymers widely used in the production of OFs; however, studies evaluating the maintenance of the active principles’ activity are incipien...

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Detalles Bibliográficos
Autores:	Remedio, Leandro Neodini, Garcia, Vitor Augusto dos Santos [UNESP], Rochetti, Arina Lazaro, Berretta, Andresa Aparecida, Ferreira, Julieta Adriana, Fukumasu, Heidge, Vanin, Fernanda Maria, Yoshida, Cristiana Maria Pedroso, de Carvalho, Rosemary Aparecida
Tipo de recurso:	artículo
Estado:	Versión publicada
Fecha de publicación:	2024
País:	Brasil
Institución:	Universidade Estadual Paulista (UNESP)
Repositorio:	Repositório Institucional da UNESP
Idioma:	inglés
OAI Identifier:	oai:repositorio.unesp.br:11449/308407
Acceso en línea:	http://dx.doi.org/10.3390/polym16131811 https://hdl.handle.net/11449/308407
Access Level:	acceso abierto
Palabra clave:	printing layers roughness stability tape casting

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spelling	Oral Films Printed with Green Propolis Ethanolic Extractprinting layersroughnessstabilitytape castingOral film (OF) research has intensified due to the effortless administration and advantages related to absorption in systemic circulation. Chitosan is one of the polymers widely used in the production of OFs; however, studies evaluating the maintenance of the active principles’ activity are incipient. Propolis has been widely used as an active compound due to its different actions. Printing techniques to incorporate propolis in OFs prove to be efficient. The objective of the present study is to develop and characterize oral films based on chitosan and propolis using printing techniques and to evaluate the main activities of the extract incorporated into the polymeric matrix. The OFs were characterized in relation to the structure using scanning and atomic force electron microscopy; the mechanical properties, disintegration time, wettability, and stability of antioxidant activity were evaluated. The ethanolic extract of green propolis (GPEE) concentration influenced the properties of the OFs. The stability (phenolic compounds and antioxidant activity) was reduced in the first 20 days, and after this period, it remained constant.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Faculty of Animal Science and Food Engineering USP—University of São Paulo, Av. Duque de Caxias Norte 225, SPFaculty of Agricultural Sciences UNESP—São Paulo State University, José Barbosa de Barros 1780, SPResearch Development & Innovation Department Apis Flora Industrial e Comercial Ltda, Rua Triunfo 945, SPFHO—Hermínio Ometto Foundation, Av. Doutor Maximiliano Baruto 500, SPInstitute of Environmental Chemical and Pharmaceutical Sciences UNIFESP—Federal University of São Paulo, Rua São Nicolau 210, SFaculty of Agricultural Sciences UNESP—São Paulo State University, José Barbosa de Barros 1780, SPCNPq: 424106/2018-3Universidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Apis Flora Industrial e Comercial LtdaFHO—Hermínio Ometto Foundation2025-04-29T20:12:23Z2024-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/polym16131811Polymers, v. 16, n. 13, 2024.2073-4360https://hdl.handle.net/11449/30840710.3390/polym161318112-s2.0-85198443539Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPolymersinfo:eu-repo/semantics/openAccessRemedio, Leandro NeodiniGarcia, Vitor Augusto dos Santos [UNESP]Rochetti, Arina LazaroBerretta, Andresa AparecidaFerreira, Julieta AdrianaFukumasu, HeidgeVanin, Fernanda MariaYoshida, Cristiana Maria Pedrosode Carvalho, Rosemary Aparecida2025-04-30T14:00:49Zoai:repositorio.unesp.br:11449/308407Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462025-04-30T14:00:49Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv	Oral Films Printed with Green Propolis Ethanolic Extract
title	Oral Films Printed with Green Propolis Ethanolic Extract
spellingShingle	Oral Films Printed with Green Propolis Ethanolic Extract Remedio, Leandro Neodini printing layers roughness stability tape casting
title_short	Oral Films Printed with Green Propolis Ethanolic Extract
title_full	Oral Films Printed with Green Propolis Ethanolic Extract
title_fullStr	Oral Films Printed with Green Propolis Ethanolic Extract
title_full_unstemmed	Oral Films Printed with Green Propolis Ethanolic Extract
title_sort	Oral Films Printed with Green Propolis Ethanolic Extract
dc.creator.none.fl_str_mv	Remedio, Leandro Neodini Garcia, Vitor Augusto dos Santos [UNESP] Rochetti, Arina Lazaro Berretta, Andresa Aparecida Ferreira, Julieta Adriana Fukumasu, Heidge Vanin, Fernanda Maria Yoshida, Cristiana Maria Pedroso de Carvalho, Rosemary Aparecida
author	Remedio, Leandro Neodini
author_facet	Remedio, Leandro Neodini Garcia, Vitor Augusto dos Santos [UNESP] Rochetti, Arina Lazaro Berretta, Andresa Aparecida Ferreira, Julieta Adriana Fukumasu, Heidge Vanin, Fernanda Maria Yoshida, Cristiana Maria Pedroso de Carvalho, Rosemary Aparecida
author_role	author
author2	Garcia, Vitor Augusto dos Santos [UNESP] Rochetti, Arina Lazaro Berretta, Andresa Aparecida Ferreira, Julieta Adriana Fukumasu, Heidge Vanin, Fernanda Maria Yoshida, Cristiana Maria Pedroso de Carvalho, Rosemary Aparecida
author2_role	author author author author author author author author
dc.contributor.none.fl_str_mv	Universidade de São Paulo (USP) Universidade Estadual Paulista (UNESP) Apis Flora Industrial e Comercial Ltda FHO—Hermínio Ometto Foundation
dc.subject.por.fl_str_mv	printing layers roughness stability tape casting
topic	printing layers roughness stability tape casting
description	Oral film (OF) research has intensified due to the effortless administration and advantages related to absorption in systemic circulation. Chitosan is one of the polymers widely used in the production of OFs; however, studies evaluating the maintenance of the active principles’ activity are incipient. Propolis has been widely used as an active compound due to its different actions. Printing techniques to incorporate propolis in OFs prove to be efficient. The objective of the present study is to develop and characterize oral films based on chitosan and propolis using printing techniques and to evaluate the main activities of the extract incorporated into the polymeric matrix. The OFs were characterized in relation to the structure using scanning and atomic force electron microscopy; the mechanical properties, disintegration time, wettability, and stability of antioxidant activity were evaluated. The ethanolic extract of green propolis (GPEE) concentration influenced the properties of the OFs. The stability (phenolic compounds and antioxidant activity) was reduced in the first 20 days, and after this period, it remained constant.
publishDate	2024
dc.date.none.fl_str_mv	2024-07-01 2025-04-29T20:12:23Z
dc.type.status.fl_str_mv	info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv	info:eu-repo/semantics/article
format	article
status_str	publishedVersion
dc.identifier.uri.fl_str_mv	http://dx.doi.org/10.3390/polym16131811 Polymers, v. 16, n. 13, 2024. 2073-4360 https://hdl.handle.net/11449/308407 10.3390/polym16131811 2-s2.0-85198443539
url	http://dx.doi.org/10.3390/polym16131811 https://hdl.handle.net/11449/308407
identifier_str_mv	Polymers, v. 16, n. 13, 2024. 2073-4360 10.3390/polym16131811 2-s2.0-85198443539
dc.language.iso.fl_str_mv	eng
language	eng
dc.relation.none.fl_str_mv	Polymers
dc.rights.driver.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.source.none.fl_str_mv	Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP
instname_str	Universidade Estadual Paulista (UNESP)
instacron_str	UNESP
institution	UNESP
reponame_str	Repositório Institucional da UNESP
collection	Repositório Institucional da UNESP
repository.name.fl_str_mv	Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv	repositoriounesp@unesp.br
_version_	1853671430236930048
score	15,300719

Oral Films Printed with Green Propolis Ethanolic Extract

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