Might anxiety disorders promote head and neck cancer development?
Cancer patients present a higher risk of experiencing anxiety disorders (AD). However, it is not clear if AD might be associated with cancer development. Thus, our study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma (HNSCC) development. The combination of an appli...
| Autores: | , , , , , , , , , , |
|---|---|
| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2020 |
| País: | Brasil |
| Recursos: | Universidade Federal de Minas Gerais (UFMG) |
| Repositório: | Repositório Institucional da UFMG |
| Idioma: | inglês |
| OAI Identifier: | oai:repositorio.ufmg.br:1843/44946 |
| Acesso em linha: | https://doi.org/10.1016/j.ibror.2020.06.001 http://hdl.handle.net/1843/44946 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Transtornos da ansiedade Cabeça - Câncer Pescoço - Câncer Carcinoma de células escamosas Tumores |
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Might anxiety disorders promote head and neck cancer development?Transtornos da ansiedadeCabeça - CâncerPescoço - CâncerCarcinoma de células escamosasTumoresCancer patients present a higher risk of experiencing anxiety disorders (AD). However, it is not clear if AD might be associated with cancer development. Thus, our study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma (HNSCC) development. The combination of an applied animal basic study and a retrospective diagnostic case and control study in patients was performed. As a result, we obtained that stress reduced the locomotor activity of the animals in the group stress and stress + 4NqO (p < 0.0001). The stress showed no influence on the progression of neoplasia in mice. In the same way, the case group did not present differences in anxiety scores in comparison to control. Moreover, no association between HNSCC staging and anxiety scores was observed. In conclusion, our in vivo findings in humans and animals have shown that there is no relationship between AD and oral squamous cell carcinoma.CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorUniversidade Federal de Minas GeraisBrasilICA - INSTITUTO DE CIÊNCIAS AGRÁRIASUFMG2022-09-06T14:09:10Z2022-09-06T14:09:10Z2020-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.1016/j.ibror.2020.06.0012451-8301http://hdl.handle.net/1843/44946engIBRO Reportsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGMarcela Gonçalvesde SouzaEmisael Stênio Batista GomesLorena Barbosa CostaAmanda Dias Silva AndradeSabrina Ferreira de JesusDaniela Paola Santos de PaulaRogério Gonçalves da RochaSérgio Henrique Sousa SantosAlfredo Maurício Batista de PaulaLucyana Conceição FariasAndré Luiz Sena Guimarães2022-09-06T14:09:10Zoai:repositorio.ufmg.br:1843/44946Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2022-09-06T14:09:10Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
| dc.title.none.fl_str_mv |
Might anxiety disorders promote head and neck cancer development? |
| title |
Might anxiety disorders promote head and neck cancer development? |
| spellingShingle |
Might anxiety disorders promote head and neck cancer development? Marcela Gonçalvesde Souza Transtornos da ansiedade Cabeça - Câncer Pescoço - Câncer Carcinoma de células escamosas Tumores |
| title_short |
Might anxiety disorders promote head and neck cancer development? |
| title_full |
Might anxiety disorders promote head and neck cancer development? |
| title_fullStr |
Might anxiety disorders promote head and neck cancer development? |
| title_full_unstemmed |
Might anxiety disorders promote head and neck cancer development? |
| title_sort |
Might anxiety disorders promote head and neck cancer development? |
| dc.creator.none.fl_str_mv |
Marcela Gonçalvesde Souza Emisael Stênio Batista Gomes Lorena Barbosa Costa Amanda Dias Silva Andrade Sabrina Ferreira de Jesus Daniela Paola Santos de Paula Rogério Gonçalves da Rocha Sérgio Henrique Sousa Santos Alfredo Maurício Batista de Paula Lucyana Conceição Farias André Luiz Sena Guimarães |
| author |
Marcela Gonçalvesde Souza |
| author_facet |
Marcela Gonçalvesde Souza Emisael Stênio Batista Gomes Lorena Barbosa Costa Amanda Dias Silva Andrade Sabrina Ferreira de Jesus Daniela Paola Santos de Paula Rogério Gonçalves da Rocha Sérgio Henrique Sousa Santos Alfredo Maurício Batista de Paula Lucyana Conceição Farias André Luiz Sena Guimarães |
| author_role |
author |
| author2 |
Emisael Stênio Batista Gomes Lorena Barbosa Costa Amanda Dias Silva Andrade Sabrina Ferreira de Jesus Daniela Paola Santos de Paula Rogério Gonçalves da Rocha Sérgio Henrique Sousa Santos Alfredo Maurício Batista de Paula Lucyana Conceição Farias André Luiz Sena Guimarães |
| author2_role |
author author author author author author author author author author |
| dc.subject.por.fl_str_mv |
Transtornos da ansiedade Cabeça - Câncer Pescoço - Câncer Carcinoma de células escamosas Tumores |
| topic |
Transtornos da ansiedade Cabeça - Câncer Pescoço - Câncer Carcinoma de células escamosas Tumores |
| description |
Cancer patients present a higher risk of experiencing anxiety disorders (AD). However, it is not clear if AD might be associated with cancer development. Thus, our study aimed to evaluate if AD might be related to head and neck squamous cell carcinoma (HNSCC) development. The combination of an applied animal basic study and a retrospective diagnostic case and control study in patients was performed. As a result, we obtained that stress reduced the locomotor activity of the animals in the group stress and stress + 4NqO (p < 0.0001). The stress showed no influence on the progression of neoplasia in mice. In the same way, the case group did not present differences in anxiety scores in comparison to control. Moreover, no association between HNSCC staging and anxiety scores was observed. In conclusion, our in vivo findings in humans and animals have shown that there is no relationship between AD and oral squamous cell carcinoma. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020-12 2022-09-06T14:09:10Z 2022-09-06T14:09:10Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://doi.org/10.1016/j.ibror.2020.06.001 2451-8301 http://hdl.handle.net/1843/44946 |
| url |
https://doi.org/10.1016/j.ibror.2020.06.001 http://hdl.handle.net/1843/44946 |
| identifier_str_mv |
2451-8301 |
| dc.language.iso.fl_str_mv |
eng |
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eng |
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IBRO Reports |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Universidade Federal de Minas Gerais Brasil ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS UFMG |
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Universidade Federal de Minas Gerais Brasil ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS UFMG |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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Universidade Federal de Minas Gerais (UFMG) |
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UFMG |
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UFMG |
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Repositório Institucional da UFMG |
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Repositório Institucional da UFMG |
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Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG) |
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repositorio@ufmg.br |
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15.300719 |