Estudo comparativo da identificacao de isquemia miocardica pela cineventriculografia contrastada sob o efeito de mononitrato de isossorbitol e pela cintilografia miocardica perfusional em portadores de cardiopatia isquemica

Objective – To evaluate and compare the usefulness of cineventriculographies, before and after nitrate use, to technetium-99m sestamibi scintigraphy for the identification of myocardial ischemia. Methods – Twenty-six patients were studied at basal conditions and 5 minutes after intravenous administr...

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Detalles Bibliográficos
Autores: Ludwig, Roberto Telles de Freitas, Kirschnick, Luciana Schmidt, Souza, Josiane de, Ribeiro, Leticia Weiss, Ordovas, Karen Gomes, Leitão, Cristiane Bauermann, Cruz, Rosana, Candiago, Rafael Henriques
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1999
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Repositório Institucional da UFRGS
Idioma:portugués
OAI Identifier:oai:www.lume.ufrgs.br:10183/19304
Acceso en línea:http://hdl.handle.net/10183/19304
Access Level:acceso abierto
Palabra clave:Isquemia miocárdica
Cintilografia
Dinitrato de isossorbida
Myocardial ischemia
Myocardial scintigraphy
Contrast ventriculography
Descripción
Sumario:Objective – To evaluate and compare the usefulness of cineventriculographies, before and after nitrate use, to technetium-99m sestamibi scintigraphy for the identification of myocardial ischemia. Methods – Twenty-six patients were studied at basal conditions and 5 minutes after intravenous administration of isosorbide mononitrate (0.3mg/kg), to evaluate the performance and regional wall motion of the left ventricle (LV). The results were compared to those obtained with technetium- 99m sestamibi scintigraphy. Results – Before nitrate, contrast ventriculography identified 30 normal segments, 62 hypokinetic segments, 28 dyskinetic segments, and 14 akinetic segments. After drug administration, 99 segments were normal, 11 hypokinetic, 11 dyskinetic, and 13 akinetic. Myocardial scintigraphy revealed 110 ischemic segments and 18 fibrotic segments (p<0.005). After drug administration, the ventriculography showed increase in the velocity of circumferential fiber shortening (p=0.0142), the ejection fraction (p=0.0462), decrease in the end-systolic volume (p=0.0031) and no change in end-diastolic volume. Conclusion – Contrast ventriculography using nitrate proved to be similar to perfusional myocardial scintigraphy in the identification of myocardial ischemia.