Espresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastáticos y no metastáticos

The aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry ana...

Descripción completa

Detalles Bibliográficos
Autores: Nardi, Andrigo Barboza de [UNESP], Daleck, Carlos Roberto [UNESP], Amorim, Renee Laufer [UNESP], Huppes, Rafael Ricardo [UNESP], Uscategui, R. A. R. [UNESP], Rodaski, Sueli, Calderón, Celmira, Torres Neto, Rafael [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:español
OAI Identifier:oai:repositorio.unesp.br:11449/136964
Acceso en línea:http://dx.doi.org/10.4067/S0301-732X2013000300012
http://hdl.handle.net/11449/136964
Access Level:acceso abierto
Palabra clave:Cancer
Mammary neoplasm
Ciclooxigenase-2
Dogs
Cáncer
Neoplasia mamaria
Ciclooxigenasa-2
Perros
Descripción
Sumario:The aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P < 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.

Similares en LA Referencia