Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)
The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic pot...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2008 |
| País: | Brasil |
| Institución: | Universidade Estadual de Maringá (UEM) |
| Repositorio: | Acta Scientiarum Biological Sciences |
| Idioma: | portugués |
| OAI Identifier: | oai:periodicos.uem.br/ojs:article/2729 |
| Acceso en línea: | http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/2729 |
| Access Level: | acceso abierto |
| Palabra clave: | Pfaffia glomerata Amaranthaceae antihiperglicemiante beta-ecdisona 2.00.00.00-6 Ciências Biológicas |
| Sumario: | The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effect |
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