Effect of physical exercise on lipid metabolism in rats submitted to hypercholesterolemic diet.

The so-called dislipedemias have been appointed as a factor causing chronic degenerative diseases as Coronarian Arterial Disease (CAD) and other aterosclerotic diseases. Hypercholesterolemia is a kind of dislipidemia characterized by a high concentration of LDL serum cholesterol, causing aterogenesi...

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Detalles Bibliográficos
Autores: Gonçalves, Allan Cristian, Oliveira, Emerson Cruz de, Pedrosa, Maria Lúcia, Silva, Marcelo Eustáquio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Brasil
Institución:Universidade Federal de Ouro Preto (UFOP)
Repositorio:Repositório Institucional da UFOP
Idioma:inglés
OAI Identifier:oai:repositorio.ufop.br:123456789/8001
Acceso en línea:http://www.repositorio.ufop.br/handle/123456789/8001
Access Level:acceso abierto
Palabra clave:Dislipidemia
Descripción
Sumario:The so-called dislipedemias have been appointed as a factor causing chronic degenerative diseases as Coronarian Arterial Disease (CAD) and other aterosclerotic diseases. Hypercholesterolemia is a kind of dislipidemia characterized by a high concentration of LDL serum cholesterol, causing aterogenesis and increasing the risk of CAD. Physicalactivity has been demonstratedto act beneficially on the factors leading to chronic degenerative diseases and having its effect potentialized when combined with a balanced diet. In the present work 48 female Fisher adult rats were distributed into four groups: Execice (swimming 30 min/day, 5 days/week) with Hypercholesterolemic Diet, Exercice with Control Diet, Sedentary with Hypercholesterolemic Diet and Sedentary with Control Diet. After 9 weeks the animals were sacrificed. The obtained results show that exercice was efficient in reducing total cholesterol, influenced in the wheight of soleo muscle and there was indication of effect on the oxidative stress as shown by increase in the concentration reduction of paraoxonase activity.The results indicate that low intensity training is capable of alter profile and suggest that new studies be made with different volumes and intensities of training.