Use of sevelamer hydrochloride and calcium carbonate in the control of hyperphosphatemia in patients in hemodialysis

To evaluate the effectiveness of sevelamer and calcium carbonate as phosphate binder. METHODS: We selected 31 patients (55±14 years) who underwent haemodyalisis (HD) 3 times / week 4 h / session, which were raised test results in zero time and end time, split into 3 groups: GI: in use of calcium car...

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Detalles Bibliográficos
Autores: de Deus, Rogério Barbosa, Malagutti, William, Ferraz, Renato Ribeiro Nogueira
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Institución:Universidade Nove de Julho (UNINOVE)
Repositorio:Revista Conscientiae Saúde (Online)
Idioma:portugués
OAI Identifier:oai:ojs.periodicos.uninove.br:article/1734
Acceso en línea:https://periodicos.uninove.br/saude/article/view/1734
Access Level:acceso abierto
Palabra clave:Carbonato de cálcio
Doença renal crônica classe V
Hiperparatireoidismo secundário
Sevelamer.
Descripción
Sumario:To evaluate the effectiveness of sevelamer and calcium carbonate as phosphate binder. METHODS: We selected 31 patients (55±14 years) who underwent haemodyalisis (HD) 3 times / week 4 h / session, which were raised test results in zero time and end time, split into 3 groups: GI: in use of calcium carbonate; GII: in use of sevelamer; GIII: without the use of phosphate binders. The GII showed a trend for higher number of extra sessions of dialysis and longer HD versus GI. The level of calcium tended to be different in GII vs GI. There was a trend for higher initial level of phosphorus GII vs GIII. Sevelamer has great therapeutic value and is of paramount importance to CKD V patients on dialysis hypercalcemic. There is evidence that in the long term, the use of sevelamer bring benefits in reducing the morbidity associated with haemodialysis.