Comparative vibrational spectra of pilosine and epiisopilosine crystals

This paper describes the study of two alkaloids extracted from Pilocarpus Microphyllus (Rutaceae): pilosine and epiisopilosine. These substances have potential application in the treatment of several diseases. In this work FT-Raman and the FT-IR spectra of pilosine and epiisopilosine were investigat...

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Detalles Bibliográficos
Autores: Bento, R. R. F., Silva, L. E. da, Faria, J. L. B., Freire, P. T. C., Oliveira, M. C. F. de, Romero, N. R., Teixeira, A. M. R., Pontes, Fenelon Martinho Lima [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/29762
Acceso en línea:http://dx.doi.org/10.1590/S0103-97332010000200016
http://hdl.handle.net/11449/29762
Access Level:acceso abierto
Palabra clave:Raman scattering
infrared spectroscopy
normal modes
pilosine
epiisopilosine
Descripción
Sumario:This paper describes the study of two alkaloids extracted from Pilocarpus Microphyllus (Rutaceae): pilosine and epiisopilosine. These substances have potential application in the treatment of several diseases. In this work FT-Raman and the FT-IR spectra of pilosine and epiisopilosine were investigated at 300 K. Vibrational wavenumber and wave vector have been predicted using density functional theory (B3LYP) calculations with the 6-31 G(d,p) basis set. A comparison with experiment, allowed us to assign most of the normal modes of the crystals.