Error in pharmaceutical compounding of alprazolam capsules

The increase of pharmaceutical drugs formulations consumption by Brazilian population demanded a greater action from the official laboratory to verify the conformity of these products, as the majority of them are composed by anxiolytics. This study reports a serious manipulation error in preparing a...

Descripción completa

Detalles Bibliográficos
Autores: Trujillo, Luz Marina, Batistic-Longatto, Mônica A., Zorzetto, Maria Ângela P., Franciosi, Sueli O.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:Brasil
Institución:Instituto Adolfo Lutz
Repositorio:Revista do Instituto Adolfo Lutz (Online)
Idioma:portugués
OAI Identifier:oai:ojs.periodicos.saude.sp.gov.br:article/32812
Acceso en línea:https://periodicos.saude.sp.gov.br/RIAL/article/view/32812
Access Level:acceso abierto
Palabra clave:alprazolam
benzodiazepine
pharmaceutical compounded preparation
benzodiazepina
medicamento manipulado
Descripción
Sumario:The increase of pharmaceutical drugs formulations consumption by Brazilian population demanded a greater action from the official laboratory to verify the conformity of these products, as the majority of them are composed by anxiolytics. This study reports a serious manipulation error in preparing alprazolam capsules formulation, where the chlordiazepoxide was placed instead of alprazolam, being both drugs belonged to therapeutic class of the benzodiazepines. A warning on the importance of manipulation process control of drugs is presented.