Herpes simplex: clinical update, epidemiology and therapeutics
Herpes is an infection caused by two viruses in the Herpesviridae family (herpes simplex types 1 and 2; HSV-1 and HSV-2), which presents a variable clinical course and for which there is currently no cure. The manifestations of HSV-1 infection include primary and recurrent orofacial herpes simplex,...
| Autores: | , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Brasil |
| Institución: | Sociedade Brasileira de Doenças Sexualmente Transmissíveis |
| Repositorio: | DST (Niterói. Online) |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs.bjstd.org:article/1089 |
| Acceso en línea: | https://www.bjstd.org/revista/article/view/1089 |
| Access Level: | acceso abierto |
| Palabra clave: | HSV-1 herpesvírus simples tipo 1 antígeno leucocitário humano (HLA) complexo maior de histocompatibilidade (MHC) DST herpes simplex virus type 1 human leukocyte antigen (HLA) major histocompatibility complex (MHC) STD |
| Sumario: | Herpes is an infection caused by two viruses in the Herpesviridae family (herpes simplex types 1 and 2; HSV-1 and HSV-2), which presents a variable clinical course and for which there is currently no cure. The manifestations of HSV-1 infection include primary and recurrent orofacial herpes simplex, while HSV-2 infection usually manifests in the form of genital herpes simplex, although cases of genital lesions from HSV-1 infection and oral lesions form HSV-2 infection can occur. Infections by the herpes simplex virus (HSV-1 and HSV-2) represent one of the most common sexually transmitted diseases globally, reaching a serum prevalence of 80% in adults. In this review of the literature, we discuss the clinical aspects of HSV infection, including epidemiology, etiology, clinical manifestations, diagnosis and treatment, as well as a brief description of the immunogenetics of HSV infection. |
|---|