Herpes simplex: clinical update, epidemiology and therapeutics
Herpes is an infection caused by two viruses in the Herpesviridae family (herpes simplex types 1 and 2; HSV-1 and HSV-2), which presents a variable clinical course and for which there is currently no cure. The manifestations of HSV-1 infection include primary and recurrent orofacial herpes simplex,...
| Authors: | , , , , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2012 |
| Country: | Brasil |
| Institution: | Sociedade Brasileira de Doenças Sexualmente Transmissíveis |
| Repository: | DST (Niterói. Online) |
| Language: | Portuguese |
| OAI Identifier: | oai:ojs.bjstd.org:article/1089 |
| Online Access: | https://www.bjstd.org/revista/article/view/1089 |
| Access Level: | Open access |
| Keyword: | HSV-1 herpesvírus simples tipo 1 antígeno leucocitário humano (HLA) complexo maior de histocompatibilidade (MHC) DST herpes simplex virus type 1 human leukocyte antigen (HLA) major histocompatibility complex (MHC) STD |
| Summary: | Herpes is an infection caused by two viruses in the Herpesviridae family (herpes simplex types 1 and 2; HSV-1 and HSV-2), which presents a variable clinical course and for which there is currently no cure. The manifestations of HSV-1 infection include primary and recurrent orofacial herpes simplex, while HSV-2 infection usually manifests in the form of genital herpes simplex, although cases of genital lesions from HSV-1 infection and oral lesions form HSV-2 infection can occur. Infections by the herpes simplex virus (HSV-1 and HSV-2) represent one of the most common sexually transmitted diseases globally, reaching a serum prevalence of 80% in adults. In this review of the literature, we discuss the clinical aspects of HSV infection, including epidemiology, etiology, clinical manifestations, diagnosis and treatment, as well as a brief description of the immunogenetics of HSV infection. |
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