Adverse drug reactions at a university hospital in Brazil

p. 40-45

Detalles Bibliográficos
Autores: Toledo, Leonardo Augusto Kister de, Noblat, Lúcia de Araújo Costa Beisl, Noblat, Antonio Carlos Beisl, Oliveira, M. G., Santos, P. M.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Institución:Universidade Federal da Bahia (UFBA)
Repositorio:Repositório Institucional da UFBA
Idioma:inglés
OAI Identifier:oai:repositorio.ufba.br:ri/1955
Acceso en línea:http://www.repositorio.ufba.br/ri/handle/ri/1955
Access Level:acceso abierto
Palabra clave:Farmacovigilância
Reações adversas
Medicamentos
Efeitos dversos
Pharmacovigilance
Adverse drug reactions
Medicines
Side effects
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dc.title.pt_BR.fl_str_mv Adverse drug reactions at a university hospital in Brazil
dc.title.alternative.pt_BR.fl_str_mv Revista de Ciências Médicas e Biológicas
title Adverse drug reactions at a university hospital in Brazil
spellingShingle Adverse drug reactions at a university hospital in Brazil
Toledo, Leonardo Augusto Kister de
Farmacovigilância
Reações adversas
Medicamentos
Efeitos dversos
Pharmacovigilance
Adverse drug reactions
Medicines
Side effects
title_short Adverse drug reactions at a university hospital in Brazil
title_full Adverse drug reactions at a university hospital in Brazil
title_fullStr Adverse drug reactions at a university hospital in Brazil
title_full_unstemmed Adverse drug reactions at a university hospital in Brazil
title_sort Adverse drug reactions at a university hospital in Brazil
dc.creator.none.fl_str_mv Toledo, Leonardo Augusto Kister de
Noblat, Lúcia de Araújo Costa Beisl
Noblat, Antonio Carlos Beisl
Oliveira, M. G.
Santos, P. M.
Toledo, Leonardo Augusto Kister de
Noblat, Lúcia de Araújo Costa Beisl
Noblat, Antonio Carlos Beisl
Oliveira, M. G.
Santos, P. M.
author Toledo, Leonardo Augusto Kister de
author_facet Toledo, Leonardo Augusto Kister de
Noblat, Lúcia de Araújo Costa Beisl
Noblat, Antonio Carlos Beisl
Oliveira, M. G.
Santos, P. M.
author_role author
author2 Noblat, Lúcia de Araújo Costa Beisl
Noblat, Antonio Carlos Beisl
Oliveira, M. G.
Santos, P. M.
author2_role author
author
author
author
dc.subject.por.fl_str_mv Farmacovigilância
Reações adversas
Medicamentos
Efeitos dversos
Pharmacovigilance
Adverse drug reactions
Medicines
Side effects
topic Farmacovigilância
Reações adversas
Medicamentos
Efeitos dversos
Pharmacovigilance
Adverse drug reactions
Medicines
Side effects
description p. 40-45
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2011-07-23T20:23:31Z
dc.date.available.fl_str_mv 2011-07-23T20:23:31Z
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/1955
dc.identifier.issn.none.fl_str_mv 2236-5222
dc.identifier.number.pt_BR.fl_str_mv v. 9, n.1
identifier_str_mv 2236-5222
v. 9, n.1
url http://www.repositorio.ufba.br/ri/handle/ri/1955
dc.language.iso.fl_str_mv eng
language eng
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eu_rights_str_mv openAccess
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instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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spelling 2011-07-23T20:23:31Z2011-07-23T20:23:31Z20102236-5222http://www.repositorio.ufba.br/ri/handle/ri/1955v. 9, n.1p. 40-45The aim of this study is to characterize the patients and the ADR notified to a Pharmacovigilance Center at a university hospital in Brazil. The ADR rate in hospitalized patients is 10% to 20% and the frequency of hospitalization due to ADR is 0,5% to 6,5%. The ADRs contribute to the increase of length in hospitalization and costs. Patient’s exposures have an increase in the rate of mortality, although about 60% to 80% could be prevented. A descriptive study carried at a university hospital in Northeast of Brazil, where all the spontaneous notifications were analyzed during two years. For the process of notification of ADR suspicions, WHO definition was used. After receiving the notification, ADR suspicions were analyzed and the causality assessment was done by CFV staff members, using three different algorithms, and classified according to severity and type. Seventy eight ADR suspicions were spontaneously notified. The female gender represented 55% of cases. Black and mulatto races represented 70%. The most frequent organ and system affected was the skin. Medicines most frequently involved in ADR were anti-infectious agents followed by anti-parasitic agents. The causality assessment shows that the frequency of certain and probable ADRs were around 55%. ADRs severity was moderate in 41%, although more than 60% of all ADRs could be prevented. ADRs are a major problem and measures must be adopted to minimize them.Submitted by Rodrigo Meirelles (rodrigomei@ufba.br) on 2011-07-23T20:23:31Z No. of bitstreams: 1 4639-11863-3-PB farm+ícia.pdf: 111976 bytes, checksum: 1f1f97e4d640493b3d52bdf21f06581b (MD5)Made available in DSpace on 2011-07-23T20:23:31Z (GMT). No. of bitstreams: 1 4639-11863-3-PB farm+ícia.pdf: 111976 bytes, checksum: 1f1f97e4d640493b3d52bdf21f06581b (MD5) Previous issue date: 2010FarmacovigilânciaReações adversasMedicamentosEfeitos dversosPharmacovigilanceAdverse drug reactionsMedicinesSide effectsAdverse drug reactions at a university hospital in BrazilRevista de Ciências Médicas e Biológicasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessToledo, Leonardo Augusto Kister deNoblat, Lúcia de Araújo Costa BeislNoblat, Antonio Carlos BeislOliveira, M. G.Santos, P. M.Toledo, Leonardo Augusto Kister deNoblat, Lúcia de Araújo Costa BeislNoblat, Antonio Carlos BeislOliveira, M. G.Santos, P. 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