Evaluation of adverse drug reactions notifications at a public hospital in Minas Gerais
Introduction: Adverse drug reactions (ADR’s) are considered a serious public health problem, being responsible for the increase in morbidity and mortality and health costs. Objective: To know the occurrence profile and describe the characteristics of the cases of ADRs notified in a sentinel hospital...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | Brasil |
| Institución: | Fundação Oswaldo Cruz (FIOCRUZ) |
| Repositorio: | Vigilância Sanitária em Debate |
| Idioma: | portugués inglés |
| OAI Identifier: | oai:ojs.visaemdebate.incqs.fiocruz.br:article/1924 |
| Acceso en línea: | https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1924 |
| Access Level: | acceso abierto |
| Palabra clave: | Pharmacovigilance; Notifcation; Adverse Drug Reactions Farmacovigilância; Notifcação; Reações Adversas a Medicamentos |
| Sumario: | Introduction: Adverse drug reactions (ADR’s) are considered a serious public health problem, being responsible for the increase in morbidity and mortality and health costs. Objective: To know the occurrence profile and describe the characteristics of the cases of ADRs notified in a sentinel hospital in Minas Gerais. Method: Observational, descriptive and cross-sectional study, which used as a source the spreadsheet of suspected ADR’s reports from the hospital's risk management from January 2015 to December 2019. Results: 255 notifications were analyzed, the majority coming from active search (69.4%), involving 269 medications and 328 episodes of ADR’s. The sector with the highest number of notifications was the Medical Clinic (43.9%). The age range of the most affected patients was between 19-59 years (54.5%), predominantly male (50.6%) and white (54.1%). Most of the ADR's were manifested through disorders in the integumentary system (36.3%), with mild severity (63.9%), mainly due to the use of systemic anti-infectives (44.6%). Conclusion: It is concluded that the notifications of ADR’s are recurrent in the hospital and their knowledge allows to outline their clinical profile, helping to prevent them and contributing to greater patient safety. |
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