Analysis of polymorphisms in codons 11, 72 and 248 of tp53 in brazilian women with breast cancer
The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53(star)11, TP53(star)72, and TP53(star)248) in BC patien...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | Brasil |
| Institución: | Universidade Federal de São Paulo (UNIFESP) |
| Repositorio: | Repositório Institucional da UNIFESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/49551 |
| Acceso en línea: | http://dx.doi.org/10.4238/gmr.15017055 http://repositorio.unifesp.br/handle/11600/49551 |
| Access Level: | acceso abierto |
| Palabra clave: | Breast Cancer Restriction Enzymes Tp53 P53 Protein Snp Brazilian WomenGene Polymorphisms P53 Polymorphisms Association Mutations Population Risk Endometriosis Variants |
| Sumario: | The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53(star)11, TP53(star)72, and TP53(star)248) in BC patients and controls. Genomic DNA was extracted from the blood cells of 393 participants |
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