Therapeutic Indications of the Ketogenic Diet: A Integrative Review

The ketogenic diet (KD), a restrictive diet, is mainly characterized by high-fat content, low or no carbohydrate content, and low or normal protein content. This review aimed to address the main syndromes or diseases in which the therapeutic use of KD can be beneficial. One of the main clinical indi...

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Bibliographic Details
Authors: Oliveira, Natália Cíntia de, Sousa, Gleice Kelly de, Ribas Filho, Durval
Format: article
Status:Published version
Publication Date:2021
Country:Brasil
Institution:Faculdade de Medicina em São José do Rio Preto (Faceres)
Repository:MedNEXT Journal of Medical and Health Sciences
Language:English
OAI Identifier:oai:ojs2.mednext.zotarellifilhoscientificworks.com:article/41
Online Access:https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/41
Access Level:Open access
Keyword:Ketogenic diet
Epilepsy
Cancer
Obesity
Diabetes
Description
Summary:The ketogenic diet (KD), a restrictive diet, is mainly characterized by high-fat content, low or no carbohydrate content, and low or normal protein content. This review aimed to address the main syndromes or diseases in which the therapeutic use of KD can be beneficial. One of the main clinical indications of KD has been, for some time, in the treatment of epilepsy refractory to the use of medications, with satisfactory results in the control of seizures. Recently, studies have addressed the metabolism of ketone bodies caused by KD, in the adjuvant treatment of tumors and endocrine disorders, such as diabetes and obesity, with promising results. In this work, the therapeutic aspect of KD was analyzed, as an aid in the control of pre-existing diseases, and that being a very restrictive diet with controversial effects, its use may be limited and it is not advisable to maintain it for long periods or without the proper follow-up.