Cerebrospinal fluid: history, collection techniques, indications, contraindications and complications

ABSTRACT This article is based on a historical review of the medical literature with the purpose of acknowledging the historical stages and anatomical findings over the years, which led gradually to performance of the first lumbar puncture by Quincke, as well as collection techniques and analyses, a...

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Detalles Bibliográficos
Autores: Oliveira,João Paulo S., Mendes,Natalia T., Martins,Álvaro R., Sanvito,Wilson Luiz
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Brasil
Institución:Sociedade Brasileira de Patologia (SBP)
Repositorio:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
Idioma:inglés
OAI Identifier:oai:scielo:S1676-24442020000100303
Acceso en línea:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100303
Access Level:acceso abierto
Palabra clave:cerebrospinal fluid
history
spinal puncture
Descripción
Sumario:ABSTRACT This article is based on a historical review of the medical literature with the purpose of acknowledging the historical stages and anatomical findings over the years, which led gradually to performance of the first lumbar puncture by Quincke, as well as collection techniques and analyses, allowing it to be an irreplaceable diagnostic tool in daily clinical practice. Cerebrospinal fluid analyses have continued to develop and nowadays play a major role in diagnosing and understanding the physiopathology of a great variety of neurological conditions. Biomarkers and genetic sequencing have recently been the target of multiple studies and are implicated as promising diagnostic tools of a large range of diseases.