Cerebrospinal fluid: history, collection techniques, indications, contraindications and complications

ABSTRACT This article is based on a historical review of the medical literature with the purpose of acknowledging the historical stages and anatomical findings over the years, which led gradually to performance of the first lumbar puncture by Quincke, as well as collection techniques and analyses, a...

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Detalhes bibliográficos
Autores: Oliveira,João Paulo S., Mendes,Natalia T., Martins,Álvaro R., Sanvito,Wilson Luiz
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Brasil
Recursos:Sociedade Brasileira de Patologia (SBP)
Repositorio:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
Idioma:inglés
OAI Identifier:oai:scielo:S1676-24442020000100303
Acesso em linha:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442020000100303
Access Level:acceso abierto
Palavra-chave:cerebrospinal fluid
history
spinal puncture
Descrição
Resumo:ABSTRACT This article is based on a historical review of the medical literature with the purpose of acknowledging the historical stages and anatomical findings over the years, which led gradually to performance of the first lumbar puncture by Quincke, as well as collection techniques and analyses, allowing it to be an irreplaceable diagnostic tool in daily clinical practice. Cerebrospinal fluid analyses have continued to develop and nowadays play a major role in diagnosing and understanding the physiopathology of a great variety of neurological conditions. Biomarkers and genetic sequencing have recently been the target of multiple studies and are implicated as promising diagnostic tools of a large range of diseases.