Corantes vitais em cromovitrectomia

The aim of this article is to present the current data with regard to the application of vital dyes during vitreoretinal surgery, chromovitrectomy, as well as to overview the current literature regarding the properties of dyes, techniques of application, indications and complications in chromovitrec...

ver descrição completa

Detalhes bibliográficos
Autores: Dib, Eduardo [UNIFESP], Rodrigues, Eduardo Buchele [UNIFESP], Maia, Maurício [UNIFESP], Meyer, Carsten H., Penha, Fernando Marcondes [UNIFESP], Furlani, Bruno de Albuquerque [UNIFESP], Costa, Elaine de Paula Fiod [UNIFESP], Farah, Michel Eid [UNIFESP]
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Recursos:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/5361
Acesso em linha:http://dx.doi.org/10.1590/S0004-27492009000600022
http://repositorio.unifesp.br/handle/11600/5361
Access Level:acceso abierto
Palavra-chave:Vitrectomy
Vitreous body
Indocyanine green
Macular hole
Retina
Trypan blue
Coloring agents
Epiretinal membrane
Vitrectomia
Corpo vítreo
Verde de indocianina
Buraco macular
Azul tripano
Agentes corantes
Membrana epirretiniana
Descrição
Resumo:The aim of this article is to present the current data with regard to the application of vital dyes during vitreoretinal surgery, chromovitrectomy, as well as to overview the current literature regarding the properties of dyes, techniques of application, indications and complications in chromovitrectomy. A large body of published research has recently addressed the toxicity profile of indocyanine green for chromovitrectomy. Experimental data demonstrate dose-dependent toxicity of indocyanine green to various retinal cells. Newer generation vital dyes for chromovitrectomy include trypan blue, patent blue, triamcinolone acetonide, infracyanine green, sodium fluorescein, bromophenol blue, fluorometholone acetate and brilliant blue. Novel instruments may enable a selective painting of preretinal tissues during chromovitrectomy. This review suggests that the field of chromovitrectomy represents an expanding area of research. The first line agents for internal limiting membrane staining in chromovitrectomy are indocyanine green, infracyanine green, and brilliant blue. Patent blue, bromophenol blue and trypan blue arose as outstanding biostains for visualization of epiretinal membranes. Novel dyes available for chromovitrectomy deserve further investigation.