Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report
Chemotherapy drugs and radiotherapy in the head and neck region are considered possible to interfere with odontogenesis. Patients may present alterations such as tooth agenesis, shortening or root malformation, enamel hypoplasia and microdontia. Such effects do not occur in adults, as they already h...
| Autores: | , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | Brasil |
| Institución: | Universidade Federal de Itajubá (UNIFEI) |
| Repositorio: | Research, Society and Development |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/22296 |
| Acceso en línea: | https://rsdjournal.org/index.php/rsd/article/view/22296 |
| Access Level: | acceso abierto |
| Palabra clave: | Antineoplásicos Sobreviventes de Câncer Anormalidades dentárias. Supervivientes de Cáncer Anomalías dentarias. Antineoplastics Cancer Survivors Tooth abnormalities. |
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Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report Efectos dentales tardíos de la quimioterapia y la radioterapia en supervivientes de cáncer infantil: reporte de caso Efeitos dentários tardios da quimioterapia e radioterapia em sobrevivente de câncer infantil: relato de caso |
| title |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report |
| spellingShingle |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report Miranda, Poliana Gonçalves Antineoplásicos Sobreviventes de Câncer Anormalidades dentárias. Antineoplásicos Supervivientes de Cáncer Anomalías dentarias. Antineoplastics Cancer Survivors Tooth abnormalities. |
| title_short |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report |
| title_full |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report |
| title_fullStr |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report |
| title_full_unstemmed |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report |
| title_sort |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report |
| dc.creator.none.fl_str_mv |
Miranda, Poliana Gonçalves Miranda, Rafael Resende de Henriques, João César Guimaraes Guedes, Cizelene do Carmo Faleiros Veloso |
| author |
Miranda, Poliana Gonçalves |
| author_facet |
Miranda, Poliana Gonçalves Miranda, Rafael Resende de Henriques, João César Guimaraes Guedes, Cizelene do Carmo Faleiros Veloso |
| author_role |
author |
| author2 |
Miranda, Rafael Resende de Henriques, João César Guimaraes Guedes, Cizelene do Carmo Faleiros Veloso |
| author2_role |
author author author |
| dc.subject.por.fl_str_mv |
Antineoplásicos Sobreviventes de Câncer Anormalidades dentárias. Antineoplásicos Supervivientes de Cáncer Anomalías dentarias. Antineoplastics Cancer Survivors Tooth abnormalities. |
| topic |
Antineoplásicos Sobreviventes de Câncer Anormalidades dentárias. Antineoplásicos Supervivientes de Cáncer Anomalías dentarias. Antineoplastics Cancer Survivors Tooth abnormalities. |
| description |
Chemotherapy drugs and radiotherapy in the head and neck region are considered possible to interfere with odontogenesis. Patients may present alterations such as tooth agenesis, shortening or root malformation, enamel hypoplasia and microdontia. Such effects do not occur in adults, as they already have the dental structures formed. The objective of this study is to describe, through a case report, the dental alterations and implications for the clinical practice of a patient who received chemotherapy and radiotherapy in childhood. A 12- year-old female patient was diagnosed with embryonal rhabdomyosarcoma in the right parotid gland region at 5 years of age. Antineoplastic treatment consisted of IRS IV chemotherapy protocol: ifosfamide (IFO) - doxorubicin (DOXO) - etoposide (VP16) followed by vincristine - dactinomycin - cyclophosphamide (VAC) / vincristine - ifosfamide - etoposide (VIE) alternated, in addition to conventional radiotherapy, with a total dose of 45 Gy. The patient developed important dental alterations, such as root malformation in most teeth, microdontia and enamel hypoplasia, being essential the role of the dentist. Currently, after 6 years of anticancer treatment, she has regular dental follow-up. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-11-21 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/22296 10.33448/rsd-v10i15.22296 |
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https://rsdjournal.org/index.php/rsd/article/view/22296 |
| identifier_str_mv |
10.33448/rsd-v10i15.22296 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/22296/20102 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 10 No. 15; e97101522296 Research, Society and Development; Vol. 10 Núm. 15; e97101522296 Research, Society and Development; v. 10 n. 15; e97101522296 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1853659880898953216 |
| spelling |
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case reportEfectos dentales tardíos de la quimioterapia y la radioterapia en supervivientes de cáncer infantil: reporte de casoEfeitos dentários tardios da quimioterapia e radioterapia em sobrevivente de câncer infantil: relato de casoAntineoplásicosSobreviventes de CâncerAnormalidades dentárias.AntineoplásicosSupervivientes de CáncerAnomalías dentarias.AntineoplasticsCancer SurvivorsTooth abnormalities.Chemotherapy drugs and radiotherapy in the head and neck region are considered possible to interfere with odontogenesis. Patients may present alterations such as tooth agenesis, shortening or root malformation, enamel hypoplasia and microdontia. Such effects do not occur in adults, as they already have the dental structures formed. The objective of this study is to describe, through a case report, the dental alterations and implications for the clinical practice of a patient who received chemotherapy and radiotherapy in childhood. A 12- year-old female patient was diagnosed with embryonal rhabdomyosarcoma in the right parotid gland region at 5 years of age. Antineoplastic treatment consisted of IRS IV chemotherapy protocol: ifosfamide (IFO) - doxorubicin (DOXO) - etoposide (VP16) followed by vincristine - dactinomycin - cyclophosphamide (VAC) / vincristine - ifosfamide - etoposide (VIE) alternated, in addition to conventional radiotherapy, with a total dose of 45 Gy. The patient developed important dental alterations, such as root malformation in most teeth, microdontia and enamel hypoplasia, being essential the role of the dentist. Currently, after 6 years of anticancer treatment, she has regular dental follow-up.Se considera que los fármacos de quimioterapia y también la radioterapia en la cabeza y el cuello pueden interferir en la odontogénesis. Estos pacientes pueden presentar alteraciones como: agenesia dental, acortamiento o malformación radicular, hipoplasia del esmalte y microdoncia. Tales efectos no ocurren en adultos, ya que ya han formado estructuras dentales. El objetivo de este trabajo es describir, a través de un caso clínico, las alteraciones e implicaciones dentales para la práctica clínica odontológica de un paciente que recibió quimioterapia y radioterapia en la infancia. Paciente mujer de 12 años diagnosticada de rabdomiosarcoma embrionario en la región de la glándula parótida derecha a los 5 años de edad. El tratamiento antineoplásico consistió en el protocolo de quimioterapia IRS IV: ifosfamida (IFO) - doxorrubicina (DOXO) - etopósido (VP16) seguido de vincristina - dactinomicina - ciclofosfamida (VAC) / vincristina - ifosfamida - etopósido (VIE) alternando con una dosis total de 45 Gy. El paciente desarrolló importantes cambios dentales como malformación radicular en la mayoría de dientes, microdoncia e hipoplasia del esmalte, siendo fundamental la actuación del odontólogo. Actualmente, después de 6 años de tratamiento antineoplásico, se encuentra bajo cuidado dental regular.As drogas quimioterápicas e radioterapia na região de cabeça e pescoço são consideradas possíveis de interferir na odontogênese. Os pacientes podem apresentar alterações como agenesia dentária, encurtamento ou má formação radicular, hipoplasia do esmalte e microdontia. Tais efeitos não ocorrem em adultos, pois estes já estão com as estruturas dentárias formadas. O objetivo deste trabalho é descrever por meio de relato de caso as alterações dentárias e implicações para a prática clínica odontológica de uma paciente que recebeu quimioterapia e radioterapia na infância. Paciente do sexo feminino, 12 anos de idade, foi diagnosticada com rabdomiossarcoma embrionário em região de glândula parótida à direita aos 5 anos de idade. O tratamento antineoplásico consistiu de quimioterapia protocolo IRS IV: ifosfamida (IFO) - doxorrubicina (DOXO) - etoposide (VP16) seguidos de vincristina - dactinomicina - ciclofosfamida (VAC)/ vincristina - ifosfamida - etoposido (VIE) alternados, além de radioterapia convencional, com dose total de 45 Gy. A paciente desenvolveu alterações dentárias importantes como má formação radicular na maioria dos dentes, microdontia e hipoplasia de esmalte, sendo fundamental a atuação do cirurgião-dentista. Atualmente, após 6 anos do tratamento antineoplásico mantém em acompanhamento odontológico regular.Research, Society and Development2021-11-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2229610.33448/rsd-v10i15.22296Research, Society and Development; Vol. 10 No. 15; e97101522296Research, Society and Development; Vol. 10 Núm. 15; e97101522296Research, Society and Development; v. 10 n. 15; e971015222962525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/22296/20102Copyright (c) 2021 Poliana Gonçalves Miranda; Rafael Resende de Miranda; João César Guimaraes Henriques; Cizelene do Carmo Faleiros Veloso Guedeshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMiranda, Poliana Gonçalves Miranda, Rafael Resende de Henriques, João César Guimaraes Guedes, Cizelene do Carmo Faleiros Veloso2021-12-06T10:13:53Zoai:ojs.pkp.sfu.ca:article/22296Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:30.476860Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
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15,301603 |