Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives

Diaminas N-monoalquiladas foram sintetizadas e tratadas com D-ribonolactona ou D-gliconolactona. As aldonamidas resultantes foram avaliadas para atividade antimicrobiana contra S. aureus, E. coli, M. tuberculosis and C. albicans. Duas hidrazidas foram também preparadas a partir da ribonoidrazida e s...

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Detalles Bibliográficos
Autores: Reis, Roberta Cristina Novaes dos, Oda, Simone do Carmo, Almeida, Mauro Vieira de, Lourenço, Maria C. S., Vicente, Felipe R. C., Raposo, Nádia Rezende Barbosa, Trevizani, Rafael, Santos, Priscila L. C., Hyaric, Mireille Le
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Brasil
Institución:Universidade Federal de Juiz de Fora (UFJF)
Repositorio:Repositório Institucional da UFJF
Idioma:inglés
OAI Identifier:oai:hermes.cpd.ufjf.br:ufjf/8948
Acceso en línea:http://dx.doi.org/10.1590/S0103-50532008000600003
https://repositorio.ufjf.br/jspui/handle/ufjf/8948
Access Level:acceso abierto
Palabra clave:-
Antimicrobial
M. tuberculosis
Amphiphilic
Aldonamide
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network_acronym_str BR
network_name_str Brasil
repository_id_str
dc.title.pt_BR.fl_str_mv Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
title Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
spellingShingle Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
Reis, Roberta Cristina Novaes dos
-
Antimicrobial
M. tuberculosis
Amphiphilic
Aldonamide
title_short Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
title_full Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
title_fullStr Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
title_full_unstemmed Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
title_sort Synthesis and antimicrobial activity of amphiphilic carbohydrate derivatives
dc.creator.none.fl_str_mv Reis, Roberta Cristina Novaes dos
Oda, Simone do Carmo
Almeida, Mauro Vieira de
Lourenço, Maria C. S.
Vicente, Felipe R. C.
Raposo, Nádia Rezende Barbosa
Trevizani, Rafael
Santos, Priscila L. C.
Hyaric, Mireille Le
author Reis, Roberta Cristina Novaes dos
author_facet Reis, Roberta Cristina Novaes dos
Oda, Simone do Carmo
Almeida, Mauro Vieira de
Lourenço, Maria C. S.
Vicente, Felipe R. C.
Raposo, Nádia Rezende Barbosa
Trevizani, Rafael
Santos, Priscila L. C.
Hyaric, Mireille Le
author_role author
author2 Oda, Simone do Carmo
Almeida, Mauro Vieira de
Lourenço, Maria C. S.
Vicente, Felipe R. C.
Raposo, Nádia Rezende Barbosa
Trevizani, Rafael
Santos, Priscila L. C.
Hyaric, Mireille Le
author2_role author
author
author
author
author
author
author
author
dc.subject.cnpq.fl_str_mv -
topic -
Antimicrobial
M. tuberculosis
Amphiphilic
Aldonamide
dc.subject.por.fl_str_mv Antimicrobial
M. tuberculosis
Amphiphilic
Aldonamide
description Diaminas N-monoalquiladas foram sintetizadas e tratadas com D-ribonolactona ou D-gliconolactona. As aldonamidas resultantes foram avaliadas para atividade antimicrobiana contra S. aureus, E. coli, M. tuberculosis and C. albicans. Duas hidrazidas foram também preparadas a partir da ribonoidrazida e suas atividades biológicas comparadas com aquelas de análogos amida. Todos os derivados da ribonolactona mostraram ter atividade antitubercular moderada, alguns foram ativos também contra S. aureus.
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2019-02-13T14:29:24Z
dc.date.available.fl_str_mv 2019-02-13
2019-02-13T14:29:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://repositorio.ufjf.br/jspui/handle/ufjf/8948
dc.identifier.doi.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S0103-50532008000600003
url http://dx.doi.org/10.1590/S0103-50532008000600003
https://repositorio.ufjf.br/jspui/handle/ufjf/8948
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Journal of the Brazilian Chemical Society
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv -
dc.publisher.initials.fl_str_mv -
dc.publisher.country.fl_str_mv Brasil
publisher.none.fl_str_mv -
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFJF
instname:Universidade Federal de Juiz de Fora (UFJF)
instacron:UFJF
instname_str Universidade Federal de Juiz de Fora (UFJF)
instacron_str UFJF
institution UFJF
reponame_str Repositório Institucional da UFJF
collection Repositório Institucional da UFJF
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spelling 2019-02-13T14:29:24Z2019-02-132019-02-13T14:29:24Z200819610651072http://dx.doi.org/10.1590/S0103-50532008000600003https://repositorio.ufjf.br/jspui/handle/ufjf/8948Diaminas N-monoalquiladas foram sintetizadas e tratadas com D-ribonolactona ou D-gliconolactona. As aldonamidas resultantes foram avaliadas para atividade antimicrobiana contra S. aureus, E. coli, M. tuberculosis and C. albicans. Duas hidrazidas foram também preparadas a partir da ribonoidrazida e suas atividades biológicas comparadas com aquelas de análogos amida. Todos os derivados da ribonolactona mostraram ter atividade antitubercular moderada, alguns foram ativos também contra S. aureus.N-monoalkylated diamines were synthesised and treated with D-ribonolactone or D-gluconolactone. The resulting aldonamides were evaluated for their antimicrobial activity against S. aureus, E. coli, M. tuberculosis and C. albicans. Two hydrazides were also prepared from ribonohydrazide and their biological activity was compared to their amide analogues. All the ribono-derivatives displayed moderated antitubercular activity, and some of them were also active against S. aureus.eng--BrasilJournal of the Brazilian Chemical Society-AntimicrobialM. tuberculosisAmphiphilicAldonamideSynthesis and antimicrobial activity of amphiphilic carbohydrate derivativesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFJFinstname:Universidade Federal de Juiz de Fora (UFJF)instacron:UFJFReis, Roberta Cristina Novaes dosOda, Simone do CarmoAlmeida, Mauro Vieira deLourenço, Maria C. S.Vicente, Felipe R. C.Raposo, Nádia Rezende BarbosaTrevizani, RafaelSantos, Priscila L. C.Hyaric, Mireille LeTHUMBNAILSynthesis and antimicrobial activity of amphiphilic carbohydrate derivatives.pdf.jpgSynthesis and antimicrobial activity of amphiphilic carbohydrate derivatives.pdf.jpgGenerated Thumbnailimage/jpeg1630https://repositorio.ufjf.br/jspui/bitstream/ufjf/8948/4/Synthesis%20and%20antimicrobial%20activity%20of%20amphiphilic%20carbohydrate%20derivatives.pdf.jpg12fddf1e625f29df8afa7fcd86869fe5MD54ORIGINALSynthesis and antimicrobial activity of amphiphilic carbohydrate derivatives.pdfSynthesis and antimicrobial activity of amphiphilic carbohydrate derivatives.pdfapplication/pdf335843https://repositorio.ufjf.br/jspui/bitstream/ufjf/8948/1/Synthesis%20and%20antimicrobial%20activity%20of%20amphiphilic%20carbohydrate%20derivatives.pdfa6e0fdf3f0d9b1823af83af70694c0b4MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82197https://repositorio.ufjf.br/jspui/bitstream/ufjf/8948/2/license.txt000e18a5aee6ca21bb5811ddf55fc37bMD52TEXTSynthesis and antimicrobial activity of amphiphilic carbohydrate derivatives.pdf.txtSynthesis and antimicrobial activity of amphiphilic carbohydrate derivatives.pdf.txtExtracted texttext/plain32274https://repositorio.ufjf.br/jspui/bitstream/ufjf/8948/3/Synthesis%20and%20antimicrobial%20activity%20of%20amphiphilic%20carbohydrate%20derivatives.pdf.txt6c6283dfc376048594913401a3a22621MD53ufjf/89482019-06-16 12:08:36.943oai:hermes.cpd.ufjf.br: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Repositório InstitucionalPUBhttps://repositorio.ufjf.br/oai/requestopendoar:2019-06-16T15:08:36Repositório Institucional da UFJF - Universidade Federal de Juiz de Fora (UFJF)false
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