Ginger (Zingiber officinale) in the Management of Chemotherapy-Induced Nausea and Vomiting in Cancer Patients: Integrative Literature Review

Introduction: Chemotherapy-induced nausea and vomiting (CINV) are important side effects of antineoplastic treatments. Some medicinal plants have been studied in the management of these effects, such as ginger (Zingiber officinale). Objective: Review the oral use of ginger in the management of CINV...

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Detalles Bibliográficos
Autores: Ferreira, Wagner Andrade, Neves, Vivian dos Santos, Fiut, Maria Angélica, Franco, Emília Delesderrier, Rodrigues, Cláudia dos Santos Cople
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Brasil
Institución:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
Repositorio:Revista Brasileira de Cancerologia (Online)
Idioma:portugués
inglés
español
OAI Identifier:oai:rbc.inca.gov.br:article/3592
Acceso en línea:https://rbc.inca.gov.br/index.php/revista/article/view/3592
Access Level:acceso abierto
Palabra clave:neoplasias/tratamento farmacológico
gengibre/efeitos adversos
plantas medicinais
fitoterapia
neoplasms/drug therapy
ginger/adverse effects
plants, medicinal
phytotherapy
neoplasias/tratamiento farmacológico
jengibre/efectos adversos
plantas medicinales
Descripción
Sumario:Introduction: Chemotherapy-induced nausea and vomiting (CINV) are important side effects of antineoplastic treatments. Some medicinal plants have been studied in the management of these effects, such as ginger (Zingiber officinale). Objective: Review the oral use of ginger in the management of CINV in cancer patients. Method: Integrative literature review carried out at the MEDLINE database, in September 2022, utilizing the combination of the keywords “Zingiber officinale” and “Cancer”, filters were also applied to include randomized clinical trials published between 2012 and 2022. Results: In all, nine studies were analyzed. Ginger has the potential to reduce CINV in cancer patients, reflecting positively on quality-of-life, improved appetite and fatigue. The studies have not found any adverse effect after administering ginger. Conclusion: The oral use of ginger proves to be an effective strategy for the management of CINV in cancer patients, in the dosage regimen of 1 g/day of powdered ginger, and can be used as a complementary therapy along with standard antiemetic regimens.