Epidemiologia molecular de Listeria monocytogenes isoladas de diferentes fontes no Brasil

Listeria monocytogenes is an important foodborne pathogen that primarily affects pregnant women, neonates, the elderly and immune-compromised individuals, and it may cause abortion, septicemia, and meningitis. From the 13 capsular groups described, serotypes 4b, 1/2b and 1/2a are most closely relate...

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Detalhes bibliográficos
Autores: Moreno, Andrea Micke, Paixão, Renata, Moreno, Luisa Zanolli, Gobbi, Débora Dirani Sena de, Raimundo, Daniele Cristine, Ferreira, Thais Sebastiana Porfida, Hofer, Ernesto, Matte, Maria Helena, Moreno, Marina
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Brasil
Recursos:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
Repositorio:Brazilian Journal of Veterinary Research and Animal Science
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/61229
Acesso em linha:https://www.revistas.usp.br/bjvras/article/view/61229
Access Level:acceso abierto
Palavra-chave:Listeria monocytogenes
Public health
ERIC-PCR
AFLP
Saúde pública
Descrição
Resumo:Listeria monocytogenes is an important foodborne pathogen that primarily affects pregnant women, neonates, the elderly and immune-compromised individuals, and it may cause abortion, septicemia, and meningitis. From the 13 capsular groups described, serotypes 4b, 1/2b and 1/2a are most closely related to human infection. For this reason, serotyping has limited value as an epidemiological tool; thus, improved discriminatory typing methods are required to enhance knowledge of L. monocytogenes contamination and infection. The aim of this study was to characterize the genetic diversity of L. monocytogenes isolates in the pork processing industry in Sao Paulo, Brazil and human infection isolates by ERICPCR and single enzyme AFLP. Serotypes 1/2c and 4b were frequent among isolates from pork and slaughterhouse/market environments, whereas serotypes 4b and 1/2a were observed among human isolates. ERIC-PCR and AFLP revealed 34 and 31 distinct profiles, respectively, which had tendencies of separation according to serogroup and isolate origin. The genetic profiles from slaughterhouse and market environments suggest the possibility of different sources of Listeria contamination in the environment, although in certain cases, continuous contamination caused by the persistence of clonal strains is also a possibility.