High-performance liquid chromatography determination of praziquantel in tablets and raw materials
A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validat...
| Authors: | , , |
|---|---|
| Format: | article |
| Status: | Published version |
| Publication Date: | 2006 |
| Country: | Brasil |
| Institution: | Universidade Estadual Paulista (UNESP) |
| Repository: | Repositório Institucional da UNESP |
| Language: | English |
| OAI Identifier: | oai:repositorio.unesp.br:11449/69152 |
| Online Access: | http://www.latamjpharm.org/trabajos/25/4/LAJOP_25_4_2_3_PYE8T8NG83.pdf http://hdl.handle.net/11449/69152 |
| Access Level: | Open access |
| Keyword: | HPLC Praziquantel Quality control praziquantel accuracy drug formulation drug structure high performance liquid chromatography tablet formulation validation process |
| Summary: | A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validation yielded good results and included the range, linearity, precision, accuracy, specificity and recovery. |
|---|