High-performance liquid chromatography determination of praziquantel in tablets and raw materials
A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validat...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2006 |
| País: | Brasil |
| Institución: | Universidade Estadual Paulista (UNESP) |
| Repositorio: | Repositório Institucional da UNESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unesp.br:11449/69152 |
| Acceso en línea: | http://www.latamjpharm.org/trabajos/25/4/LAJOP_25_4_2_3_PYE8T8NG83.pdf http://hdl.handle.net/11449/69152 |
| Access Level: | acceso abierto |
| Palabra clave: | HPLC Praziquantel Quality control praziquantel accuracy drug formulation drug structure high performance liquid chromatography tablet formulation validation process |
| Sumario: | A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validation yielded good results and included the range, linearity, precision, accuracy, specificity and recovery. |
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