Carbapenem-resistant pseudomonas aeruginosa : clonal spread in southern Brazil and in the state of Goiás

This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-β-lactamase (MBL), at the university hospital of Florianópolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well as strains collected in other three Brazilian s...

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Detalhes bibliográficos
Autores: Scheffer, Mara Cristina, Gales, Ana Cristina, Barth, Afonso Luis, Carmo Filho, Jose Rodrigues do, Dalla-Costa, Libera Maria
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Recursos:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Repositório Institucional da UFRGS
Idioma:inglés
OAI Identifier:oai:www.lume.ufrgs.br:10183/37825
Acesso em linha:http://hdl.handle.net/10183/37825
Access Level:acceso abierto
Palavra-chave:Carbapenêmicos
Pseudomonas aeruginosa
P. aeruginosa
Carbapenem resistance
Metallo-ß-lactamase
Descrição
Resumo:This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-β-lactamase (MBL), at the university hospital of Florianópolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well as strains collected in other three Brazilian states. Among the isolates, 17 (62%) were clonal and highly related to strains from other regions of Brazil. Six clonal strains harbored the blaSPM-1 gene. The fi nding of a unique SPM-1 producer clone suggests that its dissemination has contributed to the high resistance to carbapenems in Brazilian hospitals.