Carbapenem-resistant pseudomonas aeruginosa : clonal spread in southern Brazil and in the state of Goiás

This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-β-lactamase (MBL), at the university hospital of Florianópolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well as strains collected in other three Brazilian s...

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Bibliographic Details
Authors: Scheffer, Mara Cristina, Gales, Ana Cristina, Barth, Afonso Luis, Carmo Filho, Jose Rodrigues do, Dalla-Costa, Libera Maria
Format: article
Status:Published version
Publication Date:2010
Country:Brasil
Institution:Universidade Federal do Rio Grande do Sul (UFRGS)
Repository:Repositório Institucional da UFRGS
Language:English
OAI Identifier:oai:www.lume.ufrgs.br:10183/37825
Online Access:http://hdl.handle.net/10183/37825
Access Level:Open access
Keyword:Carbapenêmicos
Pseudomonas aeruginosa
P. aeruginosa
Carbapenem resistance
Metallo-ß-lactamase
Description
Summary:This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-β-lactamase (MBL), at the university hospital of Florianópolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well as strains collected in other three Brazilian states. Among the isolates, 17 (62%) were clonal and highly related to strains from other regions of Brazil. Six clonal strains harbored the blaSPM-1 gene. The fi nding of a unique SPM-1 producer clone suggests that its dissemination has contributed to the high resistance to carbapenems in Brazilian hospitals.