Tuberculosis: an uncommon cause of cerebral venous thrombosis?

Several infectious etiologies are related to cerebral venous thrombosis (CVT), but a review of literature showed only few cases related to tuberculosis (TB), and only one with neurological manifestations.We report an unusual case of CVT related to TB and mutation in prothrombin gene. A 38-man black...

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Detalles Bibliográficos
Autores: Fiorot Júnior, José Antonio [UNIFESP], Felício, André Carvalho [UNIFESP], Fukujima, Marcia Maiumi [UNIFESP], Rodrigues, Celso Arrais [UNIFESP], Morelli, Vânia Maria [UNIFESP], Lourenco, Dayse Maria [UNIFESP], Prado, Gilmar Fernandes do [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2005
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/2660
Acceso en línea:http://dx.doi.org/10.1590/S0004-282X2005000500025
http://repositorio.unifesp.br/handle/11600/2660
Access Level:acceso abierto
Palabra clave:cerebral venous thrombosis
tuberculosis
prothrombin gene mutation
trombose venosa cerebral
tuberculose
mutação do gene da protrombina
Descripción
Sumario:Several infectious etiologies are related to cerebral venous thrombosis (CVT), but a review of literature showed only few cases related to tuberculosis (TB), and only one with neurological manifestations.We report an unusual case of CVT related to TB and mutation in prothrombin gene. A 38-man black presented abrupt right hemiparestesis, and hemiparesis. Investigations revealed CVT. Cerebral spinal fluid (CSF) examination evidenced a infection by Mycobacterium. He was heterozygous for G20210A prothrombin mutation. Probably, hypercoagulability mechanisms of TB, added to mutation of prothrombim gene increase the risk of CVT.