Cerebral sinovenous thrombosis in a nephrotic child

Nephrotic syndrome in infancy and childhood is known to be associated with a hypercoagulable state and thromboembolic complications, but cerebral sinovenous thrombosis (CST) is a very rare and serious one, with only a few isolated reports in the literature. A case is presented of a 9-year-old boy wi...

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Detalles Bibliográficos
Autores: Masruha, Marcelo Rodrigues [UNIFESP], Zardini, Lilian Rocha [UNIFESP], Andrade, Maria Cristina de [UNIFESP], Mangia, Cristina Malzoni Ferreira [UNIFESP], Carvalhaes, João Tomás de Abreu [UNIFESP], Vilanova, Luiz Celso Pereira [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/1941
Acceso en línea:http://dx.doi.org/10.1590/S0004-282X2003000600027
http://repositorio.unifesp.br/handle/11600/1941
Access Level:acceso abierto
Palabra clave:cerebral venous thrombosis
sagittal sinus thrombosis
nephrotic syndrome
child
trombose venosa cerebral
trombose do seio sagital
síndrome nefrótica
criança
Descripción
Sumario:Nephrotic syndrome in infancy and childhood is known to be associated with a hypercoagulable state and thromboembolic complications, but cerebral sinovenous thrombosis (CST) is a very rare and serious one, with only a few isolated reports in the literature. A case is presented of a 9-year-old boy with nephrotic syndrome that acutely developed signs and symptoms of intracranial hypertension syndrome. CST was diagnosed on cranial CT and MRI and he gradually recovered after treatment with anticoagulants. The diagnosis of CST should be considered in any patient with nephrotic syndrome who develops neurologic symptoms. The discussion of this case, coupled with a review of the literature, emphasizes that early diagnosis is essential for institution of anticoagulation therapy and a successful outcome. This report also illustrates the difficulties that may be encountered in managing such a patient.