Fulminant Hepatitis as the First Presentation of Wilson’s Disease

Wilson’s disease is rare, but it affects 6-12% of patients with an indication for urgent liver transplantation. The main manifestations, in addition to the liver, are neurological and psychiatric, with evolution with fulminant hepatitis without neuropsychiatric symptoms being rarer. Despite the urge...

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Detalles Bibliográficos
Autores: Frainer, Djulia Adriani, Welter, Carolina da Silveira, Theis, Claudia, Garcia, Raquel Francine Liermann, Lemos, Ricardo, Haritsch, Franco, Lima, Andre Carminati, Garcia, Christian Evangelista
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Brasil
Institución:Associação Brasileira de Transplante de Órgãos (ABTO)
Repositorio:Brazilian Journal of Transplantation
Idioma:inglés
portugués
OAI Identifier:oai:ojs3.emnuvens.com.br:article/497
Acceso en línea:https://bjt.emnuvens.com.br/revista/article/view/497
Access Level:acceso abierto
Palabra clave:Insuficiência Hepática Fulminante
Transplante de Fígado
Pseudoaneurisma
Fulminant Hepatic Insufficiency
Liver Transplantation
Pseudoaneurysm
Enfermedad de Wilson
Insuficiencia Hepática Fulminante
Trasplante de Hígado
Informes de Casos
Descripción
Sumario:Wilson’s disease is rare, but it affects 6-12% of patients with an indication for urgent liver transplantation. The main manifestations, in addition to the liver, are neurological and psychiatric, with evolution with fulminant hepatitis without neuropsychiatric symptoms being rarer. Despite the urgency, the prognosis for post-transplant patients averages 85% 5-year survival. In this report, we presentthe case of a female patient, 18 years old, with the onset of abdominal pain, jaundice and choluria that progressed to fulminanthepatitis and the need for urgent liver transplantation. The patient evolved postoperatively with septic shock due to herpetic encephalitis, duodenal ulcer with active bleeding and hepatic artery pseudoaneurysm. Despite measures for stabilization and the request for a transplant again, the patient died.