Polycystic ovary syndrome: clinical and laboratory evaluation

OBJECTIVE: To evaluate clinically, and with laboratory, tests, women with polycystic ovary syndrome (PCO). PATIENTS: One hundred and twelve women with PCO were studied. METHODS: The following data was recorded: Current age; age at menarche; menstrual irregularity, occurrence of similar cases in the...

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Detalles Bibliográficos
Autores: Khoury, Marcos Yorghi [UNIFESP], Baracat, Edmund Chada [UNIFESP], Pardini, Dolores Perovano [UNIFESP], Haidar, Mauro Abi [UNIFESP], Motta, Eduardo Leme Alves da [UNIFESP], Lima, Geraldo Rodrigues De [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1996
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/431
Acceso en línea:http://dx.doi.org/10.1590/S1516-31801996000400006
http://repositorio.unifesp.br/handle/11600/431
Access Level:acceso abierto
Palabra clave:Polycystic Ovary syndrome
Oligomenorrhea
Secondary amenorrhea
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spelling Polycystic ovary syndrome: clinical and laboratory evaluationPolycystic Ovary syndromeOligomenorrheaSecondary amenorrheaOBJECTIVE: To evaluate clinically, and with laboratory, tests, women with polycystic ovary syndrome (PCO). PATIENTS: One hundred and twelve women with PCO were studied. METHODS: The following data was recorded: Current age; age at menarche; menstrual irregularity, occurrence of similar cases in the family; fertility, obstetric history; body mass index (BMI); and presence of hirsutism. Serum measurements of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, free testosterone, and dehydroepiandrosterone sulfate were taken. RESULTS: All patients presented either oligomenorrhea (31 percent), periods of secondary amenorrhea (9 percent), or both alterations (60 percent). The majority of the patients were infertile (75.6 percent). The LH/FSH ratio was higher than 2:1 in 55 percent of the patients and higher than 3:1 in 26.2 percent. The ultrasonographic aspect of the ovaries was considered to be normal in 31 percent. CONCLUSION: The main clinical feature of the PCO is the irregularity of menses since menarche, and that the laboratory tests would be important to exclude other disorders such as hyperprolactinemia or hyperandrogenemia caused by late-onset congenital adrenal hyperplasia.OBJETIVOS: Avaliar clinica e laboratorialmente mulheres com a síndrome dos ovários policísticos (SOP). PACIENTES: Foram estudadas 112 mulheres com SOP. MÉTODOS: Avaliamos idade, idade da menarca, história menstrual, época do aparecimento da irregularidade menstrual, ocorrência de casos semelhantes na família, antecedentes obstétricos, índice de massa corpórea, e presença de hirsutismo. Foram realizadas as dosagens séricas de hormônio foliculo-estimulante (FSH), hormônio luteinizante (LH), prolactina, testosterona livre e de sulfato de dehidroepiandrosterona. RESULTADOS: Todas as mulheres apresentavam espaniomenorréia (31 percent), períodos de amenorréia secundária (9 percent) ou ambas alterações (60 percent). A maioria era infértil (75,6 percent). A relação LH/FSH era maior que 3 em 26,2 percent e maior que 2 em 55,0 percent das mulheres. O aspecto ultra-sonográfico dos ovários era normal em 31 percent das mulheres. CONCLUSÃO: A principal característica clínica da SOP é a irregularidade menstrual desde a menarca e os exames de laboratório seriam importantes para afastar outras patologias como as síndromes hiperprolactinêmicas ou as deficiências enzimáticas tardias da supra-renal.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Department of GynecologyUNIFESP, EPM, Department of GynecologySciELOAssociação Paulista de Medicina - APMUniversidade Federal de São Paulo (UNIFESP)2015-06-14T13:24:32Z2015-06-14T13:24:32Z1996-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1222-1225application/pdfhttp://dx.doi.org/10.1590/S1516-31801996000400006São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 114, n. 4, p. 1222-1225, 1996.10.1590/S1516-31801996000400006S1516-31801996000400006.pdf1516-3180S1516-31801996000400006http://repositorio.unifesp.br/handle/11600/431ark:/48912/001300002p2chengSão Paulo Medical Journalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPKhoury, Marcos Yorghi [UNIFESP]Baracat, Edmund Chada [UNIFESP]Pardini, Dolores Perovano [UNIFESP]Haidar, Mauro Abi [UNIFESP]Motta, Eduardo Leme Alves da [UNIFESP]Lima, Geraldo Rodrigues De [UNIFESP]2024-08-06T06:35:04Zoai:repositorio.unifesp.br:11600/431Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T06:35:04Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Polycystic ovary syndrome: clinical and laboratory evaluation
title Polycystic ovary syndrome: clinical and laboratory evaluation
spellingShingle Polycystic ovary syndrome: clinical and laboratory evaluation
Khoury, Marcos Yorghi [UNIFESP]
Polycystic Ovary syndrome
Oligomenorrhea
Secondary amenorrhea
title_short Polycystic ovary syndrome: clinical and laboratory evaluation
title_full Polycystic ovary syndrome: clinical and laboratory evaluation
title_fullStr Polycystic ovary syndrome: clinical and laboratory evaluation
title_full_unstemmed Polycystic ovary syndrome: clinical and laboratory evaluation
title_sort Polycystic ovary syndrome: clinical and laboratory evaluation
dc.creator.none.fl_str_mv Khoury, Marcos Yorghi [UNIFESP]
Baracat, Edmund Chada [UNIFESP]
Pardini, Dolores Perovano [UNIFESP]
Haidar, Mauro Abi [UNIFESP]
Motta, Eduardo Leme Alves da [UNIFESP]
Lima, Geraldo Rodrigues De [UNIFESP]
author Khoury, Marcos Yorghi [UNIFESP]
author_facet Khoury, Marcos Yorghi [UNIFESP]
Baracat, Edmund Chada [UNIFESP]
Pardini, Dolores Perovano [UNIFESP]
Haidar, Mauro Abi [UNIFESP]
Motta, Eduardo Leme Alves da [UNIFESP]
Lima, Geraldo Rodrigues De [UNIFESP]
author_role author
author2 Baracat, Edmund Chada [UNIFESP]
Pardini, Dolores Perovano [UNIFESP]
Haidar, Mauro Abi [UNIFESP]
Motta, Eduardo Leme Alves da [UNIFESP]
Lima, Geraldo Rodrigues De [UNIFESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.subject.por.fl_str_mv Polycystic Ovary syndrome
Oligomenorrhea
Secondary amenorrhea
topic Polycystic Ovary syndrome
Oligomenorrhea
Secondary amenorrhea
description OBJECTIVE: To evaluate clinically, and with laboratory, tests, women with polycystic ovary syndrome (PCO). PATIENTS: One hundred and twelve women with PCO were studied. METHODS: The following data was recorded: Current age; age at menarche; menstrual irregularity, occurrence of similar cases in the family; fertility, obstetric history; body mass index (BMI); and presence of hirsutism. Serum measurements of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, free testosterone, and dehydroepiandrosterone sulfate were taken. RESULTS: All patients presented either oligomenorrhea (31 percent), periods of secondary amenorrhea (9 percent), or both alterations (60 percent). The majority of the patients were infertile (75.6 percent). The LH/FSH ratio was higher than 2:1 in 55 percent of the patients and higher than 3:1 in 26.2 percent. The ultrasonographic aspect of the ovaries was considered to be normal in 31 percent. CONCLUSION: The main clinical feature of the PCO is the irregularity of menses since menarche, and that the laboratory tests would be important to exclude other disorders such as hyperprolactinemia or hyperandrogenemia caused by late-onset congenital adrenal hyperplasia.
publishDate 1996
dc.date.none.fl_str_mv 1996-08-01
2015-06-14T13:24:32Z
2015-06-14T13:24:32Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1516-31801996000400006
São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 114, n. 4, p. 1222-1225, 1996.
10.1590/S1516-31801996000400006
S1516-31801996000400006.pdf
1516-3180
S1516-31801996000400006
http://repositorio.unifesp.br/handle/11600/431
dc.identifier.dark.fl_str_mv ark:/48912/001300002p2ch
url http://dx.doi.org/10.1590/S1516-31801996000400006
http://repositorio.unifesp.br/handle/11600/431
identifier_str_mv São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 114, n. 4, p. 1222-1225, 1996.
10.1590/S1516-31801996000400006
S1516-31801996000400006.pdf
1516-3180
S1516-31801996000400006
ark:/48912/001300002p2ch
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv São Paulo Medical Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1222-1225
application/pdf
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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score 15,300724

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