Polycystic ovary syndrome: clinical and laboratory evaluation

OBJECTIVE: To evaluate clinically, and with laboratory, tests, women with polycystic ovary syndrome (PCO). PATIENTS: One hundred and twelve women with PCO were studied. METHODS: The following data was recorded: Current age; age at menarche; menstrual irregularity, occurrence of similar cases in the...

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Detalles Bibliográficos
Autores: Khoury, Marcos Yorghi [UNIFESP], Baracat, Edmund Chada [UNIFESP], Pardini, Dolores Perovano [UNIFESP], Haidar, Mauro Abi [UNIFESP], Motta, Eduardo Leme Alves da [UNIFESP], Lima, Geraldo Rodrigues De [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1996
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/431
Acceso en línea:http://dx.doi.org/10.1590/S1516-31801996000400006
http://repositorio.unifesp.br/handle/11600/431
Access Level:acceso abierto
Palabra clave:Polycystic Ovary syndrome
Oligomenorrhea
Secondary amenorrhea
Descripción
Sumario:OBJECTIVE: To evaluate clinically, and with laboratory, tests, women with polycystic ovary syndrome (PCO). PATIENTS: One hundred and twelve women with PCO were studied. METHODS: The following data was recorded: Current age; age at menarche; menstrual irregularity, occurrence of similar cases in the family; fertility, obstetric history; body mass index (BMI); and presence of hirsutism. Serum measurements of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, free testosterone, and dehydroepiandrosterone sulfate were taken. RESULTS: All patients presented either oligomenorrhea (31 percent), periods of secondary amenorrhea (9 percent), or both alterations (60 percent). The majority of the patients were infertile (75.6 percent). The LH/FSH ratio was higher than 2:1 in 55 percent of the patients and higher than 3:1 in 26.2 percent. The ultrasonographic aspect of the ovaries was considered to be normal in 31 percent. CONCLUSION: The main clinical feature of the PCO is the irregularity of menses since menarche, and that the laboratory tests would be important to exclude other disorders such as hyperprolactinemia or hyperandrogenemia caused by late-onset congenital adrenal hyperplasia.