Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids

Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be...

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Detalles Bibliográficos
Autores: Oliveira Filho, Cilomar Martins de, Vieceli, Tarsila, Bassotto, Caroline de Fraga, Barbato, João Pedro da Rosa, Garcia, Tiago Severo, Scheffel, Rafael Selbach
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Repositório Institucional da UFRGS
Idioma:inglés
OAI Identifier:oai:www.lume.ufrgs.br:10183/220413
Acceso en línea:http://hdl.handle.net/10183/220413
Access Level:acceso abierto
Palabra clave:Infecções por coronavirus
Pneumonia em organização criptogênica
Corticosteróides
COVID-19
Organizing pneumonia
Corticosteroids
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spelling 2021-05-04T04:26:28Z20211413-8670http://hdl.handle.net/10183/220413001124263Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered. Herein we report a series of three patients, one male and two females, mean age 58.3 years old, admitted for COVID-19 with severe pulmonary disease requiring ventilatory support. The patients underwent chest computed tomography scans due to maintained hypoxemia, which showed a pattern compatible with organizing pneumonia. The patients were treated with a high dose of corticosteroids (prednisone 1mg/kg PO), showing marked clinical improvement, and decreasing oxygen flow ratio demand. They were discharged after a mean period of 6.3 days of hospitalization. Our report suggests that patients with COVID-19 with organizing pneumonia might benefit from high dose corticosteroids as an adjuvant therapy.application/pdfengThe Brazilian journal of infectious diseases. Salvador. Vol. 25, no. 1 (Jan./Feb. 2021), 101541, 4 p.Infecções por coronavirusPneumonia em organização criptogênicaCorticosteróidesCOVID-19Organizing pneumoniaCorticosteroidsOrganizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroidsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSOliveira Filho, Cilomar Martins deVieceli, TarsilaBassotto, Caroline de FragaBarbato, João Pedro da RosaGarcia, Tiago SeveroScheffel, Rafael SelbachTEXT001124263.pdf.txt001124263.pdf.txtExtracted Texttext/plain12503http://www.lume.ufrgs.br/bitstream/10183/220413/2/001124263.pdf.txt0e79b9931230979ab55cf4ff51fe90ffMD52ORIGINAL001124263.pdfTexto completo (inglês)application/pdf1531389http://www.lume.ufrgs.br/bitstream/10183/220413/1/001124263.pdf713cf3f58391af9bd324f6e999bb8cbfMD5110183/2204132025-01-11 07:55:44.529552oai:www.lume.ufrgs.br:10183/220413Repositório InstitucionalPUBhttps://lume.ufrgs.br/oai/requestlume@ufrgs.bropendoar:2025-01-11T09:55:44Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
title Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
spellingShingle Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
Oliveira Filho, Cilomar Martins de
Infecções por coronavirus
Pneumonia em organização criptogênica
Corticosteróides
COVID-19
Organizing pneumonia
Corticosteroids
title_short Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
title_full Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
title_fullStr Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
title_full_unstemmed Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
title_sort Organizing pneumonia : a late phase complication of COVID-19 responding dramatically to corticosteroids
dc.creator.none.fl_str_mv Oliveira Filho, Cilomar Martins de
Vieceli, Tarsila
Bassotto, Caroline de Fraga
Barbato, João Pedro da Rosa
Garcia, Tiago Severo
Scheffel, Rafael Selbach
author Oliveira Filho, Cilomar Martins de
author_facet Oliveira Filho, Cilomar Martins de
Vieceli, Tarsila
Bassotto, Caroline de Fraga
Barbato, João Pedro da Rosa
Garcia, Tiago Severo
Scheffel, Rafael Selbach
author_role author
author2 Vieceli, Tarsila
Bassotto, Caroline de Fraga
Barbato, João Pedro da Rosa
Garcia, Tiago Severo
Scheffel, Rafael Selbach
author2_role author
author
author
author
author
dc.subject.por.fl_str_mv Infecções por coronavirus
Pneumonia em organização criptogênica
Corticosteróides
COVID-19
topic Infecções por coronavirus
Pneumonia em organização criptogênica
Corticosteróides
COVID-19
Organizing pneumonia
Corticosteroids
dc.subject.eng.fl_str_mv Organizing pneumonia
Corticosteroids
description Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered. Herein we report a series of three patients, one male and two females, mean age 58.3 years old, admitted for COVID-19 with severe pulmonary disease requiring ventilatory support. The patients underwent chest computed tomography scans due to maintained hypoxemia, which showed a pattern compatible with organizing pneumonia. The patients were treated with a high dose of corticosteroids (prednisone 1mg/kg PO), showing marked clinical improvement, and decreasing oxygen flow ratio demand. They were discharged after a mean period of 6.3 days of hospitalization. Our report suggests that patients with COVID-19 with organizing pneumonia might benefit from high dose corticosteroids as an adjuvant therapy.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-05-04T04:26:28Z
dc.date.issued.fl_str_mv 2021
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dc.identifier.issn.pt_BR.fl_str_mv 1413-8670
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dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv The Brazilian journal of infectious diseases. Salvador. Vol. 25, no. 1 (Jan./Feb. 2021), 101541, 4 p.
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