Associated factors of pneumonia in individuals with chronic obstructive pulmonary disease (COPD) apart from the use of inhaled corticosteroids

Inhaled corticosteroids (ICSs) are widely used in chronic obstructive pulmonary disease (COPD) and in combination with long-acting 2 agonists (LABAs) to reduce exacerbations and improve patient lung function and quality of life. However, ICSs have been associated with an increased risk of pneumonia...

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Detalles Bibliográficos
Autores: Lineros, Rosario, Fernández Delgado, Lourdes, Vega Rioja, Antonio, Chacón, Pedro, Doukkali, Bouchra, Monteseirin, Javier, Ribas Pérez, David
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:dnet:idus________::850d7e6643619a4937f18681761d20e0
Acceso en línea:https://hdl.handle.net/11441/169930
Access Level:acceso abierto
Palabra clave:COPD
Pneumonia
Inhaled corticosteroids
Descripción
Sumario:Inhaled corticosteroids (ICSs) are widely used in chronic obstructive pulmonary disease (COPD) and in combination with long-acting 2 agonists (LABAs) to reduce exacerbations and improve patient lung function and quality of life. However, ICSs have been associated with an increased risk of pneumonia in individuals with COPD, although the magnitude of this risk remains unclear. Therefore, it is difficult to make informed clinical decisions that balance the benefits and adverse effects of ICSs in people with COPD. There may be other causes of pneumonia in patients with COPD,andthese causes are not always considered in studies on the risks of using ICSs in COPD. Weconsider it very useful to clarify these aspects in assessing the influence of ICSs on the incidence of pneumonia and their role in the treatment of COPD. This issue has important implications for current practice and the evaluation and management of COPD, since COPD patients may benefit from specific ICS-based treatment strategies. Many of the potential causes of pneumonia in patients with COPDcanact synergistically, so they can be included in more than one section.