Haff disease: overview and clinical features

Haff disease was first described at the beginning of the twentieth century in Europe. Almost a century later, thousands of cases have now been reported in different countries. In Brazil, most cases are observed in the Amazon region, and its associated factors remain to be fully understood. This dise...

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Detalles Bibliográficos
Autores: Aguiar, Gabriel Rotsen Fortes, Silva, Roberto Cesar de Moura, Petruccelli, Karla Cristina Silva, Oliveira, Michael Nascimento, Brito, Gabriel Antônio Uchôa de, Albuquerque, Polianna Lemos Moura Moreira, Daher, Elizabeth De Francesco, Silva Junior, Geraldo Bezerra da
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Brasil
Institución:Instituto de Medicina Tropical (IMT)
Repositorio:Revista do Instituto de Medicina Tropical de São Paulo
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/230392
Acceso en línea:https://www.revistas.usp.br/rimtsp/article/view/230392
Access Level:acceso abierto
Palabra clave:Haff disease
Haff syndrome
Rhabdomyolysis
Amazon
Epidemiology
Descripción
Sumario:Haff disease was first described at the beginning of the twentieth century in Europe. Almost a century later, thousands of cases have now been reported in different countries. In Brazil, most cases are observed in the Amazon region, and its associated factors remain to be fully understood. This disease is an uncommon syndrome characterized by intense myalgia and rhabdomyolysis, which manifests within 24 h after consuming some types of freshwater or saltwater fish and crustaceans. A possible heat-stable toxin contained in seafood may be the cause of Haff disease, but this hypothesis is not yet completely proven. This review will describe the clinical and epidemiological aspects of Haff disease with updated literature.