Waste-grass-mediated green synthesis of silver nanoparticles and evaluation of their anticancer, antifungal and antibacterial activity

Grass waste was used for transform an inexpensive waste into health. Silver nanoparticles (AgNPs) have been synthesized using waste material (dried grass). The average size of silver nanoparticles observed in transmission electron images was estimated to be about 15nm. The anticancer, antifungal and...

Descripción completa

Detalles Bibliográficos
Autores: Khatami, Mehrdad, Sharifi, Iraj, Nobre, Marcos A. L. [UNESP], Zafarnia, Niloofar, Aflatoonian, Mohammad R.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/164003
Acceso en línea:http://dx.doi.org/10.1080/17518253.2018.1444797
http://hdl.handle.net/11449/164003
Access Level:acceso abierto
Palabra clave:Waste material
green synthesis
inhibitory effect
antifungal
antibacterial
nanoparticles
Descripción
Sumario:Grass waste was used for transform an inexpensive waste into health. Silver nanoparticles (AgNPs) have been synthesized using waste material (dried grass). The average size of silver nanoparticles observed in transmission electron images was estimated to be about 15nm. The anticancer, antifungal and antibacterial effect of AgNPs were studied in vitro. The minimum inhibitory concentration of AgNPs against Pseudomonas aeruginosa and Acinetobacter baumannii was calculated about 3 mu g/ml. The highest level of inhibitory effect of AgNPs against Fusarium solani was close to 90% at a concentration of 20g/ml of AgNPs. An inhibitory effect on the cancer cell growth is reach, by increasing the concentration of AgNPs to 5 mu g/ml; the cancer cells' survival decreases about 30%. Western results showed that the expression of Cyclin D1 protein of MCF-7 cell line decreased after treatment with the effective concentration of AgNPs. [GRAPHICS] .