Segmentation of Cell Nuclei Regions in Epithelium of Prostate Glands
This paper proposes a method for segmentation of cell nuclei regions in epithelium of prostate glands. This structure provides information to diagnosis and prognosis of prostate cancer. In the initial step, the contrast stretching technique was applied in image in order to improve the contrast betwe...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Brasil |
| Institución: | Universidade Estadual Paulista (UNESP) |
| Repositorio: | Repositório Institucional da UNESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unesp.br:11449/122835 |
| Acceso en línea: | http://connection.ebscohost.com/c/articles/90307465/segmentation-cell-nuclei-regions-epithelium-prostate-glands http://hdl.handle.net/11449/122835 |
| Access Level: | acceso abierto |
| Palabra clave: | Cell Nuclei Regions Segmentation Histological Segmentation Prostate Glands Digital Pathology Contrast Stretching Global Thresholding |
| Sumario: | This paper proposes a method for segmentation of cell nuclei regions in epithelium of prostate glands. This structure provides information to diagnosis and prognosis of prostate cancer. In the initial step, the contrast stretching technique was applied in image in order to improve the contrast between regions of interest and other regions. After, the global thresholding technique was applied and the value of threshold was defined empirically. Finally, the false positive regions were removed using the connected components technique. The performance of the proposed method was compared with the Otsu technique and statistical measures of accuracy were calculated based on reference images (gold standard). The result of the mean value of accuracy of proposed method was 93% ± 0.07. |
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