Six weeks of a concurrent training therapy improves endothelial function and arterial stiffness in hypertensive adults with minimum non-responders
Background: This study aimed to examine the effects of a six-week of concurrent training using high-intensity interval plus resistance training on flow-mediated dilation and pulse wave velocity in hypertensive, elevated blood pressure, or normotensive. A secondary goal was to analyze the inter-indiv...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | Brasil |
| Institución: | Universidade Estadual Paulista (UNESP) |
| Repositorio: | Repositório Institucional da UNESP |
| Idioma: | inglés español |
| OAI Identifier: | oai:repositorio.unesp.br:11449/299660 |
| Acceso en línea: | http://dx.doi.org/10.1016/j.hipert.2024.07.001 https://hdl.handle.net/11449/299660 |
| Access Level: | acceso abierto |
| Palabra clave: | Arterial hypertension Arterial stiffness Blood pressure Endothelial function Obesity |
| Sumario: | Background: This study aimed to examine the effects of a six-week of concurrent training using high-intensity interval plus resistance training on flow-mediated dilation and pulse wave velocity in hypertensive, elevated blood pressure, or normotensive. A secondary goal was to analyze the inter-individual variability. Methods: A randomized controlled clinical trial was executed with 60 adult participants distributed across six groups: three control groups of hypertensive, elevated blood pressure, or normotensive and other three experimental hypertensive, elevated blood pressure, and normotensive groups, each comprising n = 10 individuals. Participants underwent a six-week intervention of concurrent exercise using high-intensity interval plus resistance training three-weekly. Flow mediated dilation and pulse wave velocity and secondary vascular assessments were conducted before and after the intervention. Results: The hypertensive exercise group exhibited a significant increase in flow mediated dilation (Δ+7.7%; p = 0.003) and a reduction in pulse wave velocity (Δ−1.2 m s−1; p < 0.0001). The normotensive exercise group also showed a significant increase in flow mediated dilation (Δ+8.4%, p = 0.002). Conclusion: The six-week concurrent exercise using high-intensity interval plus resistance training protocol, characterized by its clinical time-efficiency, was effective in improving endothelial function, as demonstrated by increased flow mediated dilation, and in reducing arterial stiffness, indicated by decreased pulse wave velocity. |
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