Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments about a recently published concerni...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2008 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/104392 |
| Acceso en línea: | http://hdl.handle.net/11336/104392 |
| Access Level: | acceso abierto |
| Palabra clave: | Intrahepatic cholestasis of pregnancy ABCC2 MRP2 Gene variants https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 https://purl.org/becyt/ford/3.2 https://purl.org/becyt/ford/3 |
| Sumario: | The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments about a recently published concerning the role of ABCB11 and ABCC2 polymorphisms in both ICP and contraceptive-induced cholestasis, in particular at the light of our recently published findings about a positive association between ICP and ABCC2 common variants. |
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