Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics

This study describes the effects of feeding growing rats with a diet containing inadequate and incomplete proteins on both the morphological and the biomechanical properties of the mandible. Female rats aged 30 d were fed freely with one of two diets, control (CD, 301 Cal/100g) and experimental (ED,...

Descripción completa

Detalles Bibliográficos
Autores: Bozzini, Clarisa, Champin, Graciela Monica, Bozzini, Carlos Eduardo Jose, Alippi, Rosa Maria
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/1932
Acceso en línea:http://hdl.handle.net/11336/1932
Access Level:acceso abierto
Palabra clave:Mandibula
Biomécanica Osea
Nutrición
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
id AR_fb97a4e1c88fe90ee04cb47a2a111c22
oai_identifier_str oai:ri.conicet.gov.ar:11336/1932
network_acronym_str AR
network_name_str Argentina
repository_id_str
dc.title.none.fl_str_mv Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
title Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
spellingShingle Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
Bozzini, Clarisa
Mandibula
Biomécanica Osea
Nutrición
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
title_short Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
title_full Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
title_fullStr Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
title_full_unstemmed Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
title_sort Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics
dc.creator.none.fl_str_mv Bozzini, Clarisa
Champin, Graciela Monica
Bozzini, Carlos Eduardo Jose
Alippi, Rosa Maria
author Bozzini, Clarisa
author_facet Bozzini, Clarisa
Champin, Graciela Monica
Bozzini, Carlos Eduardo Jose
Alippi, Rosa Maria
author_role author
author2 Champin, Graciela Monica
Bozzini, Carlos Eduardo Jose
Alippi, Rosa Maria
author2_role author
author
author
dc.subject.none.fl_str_mv Mandibula
Biomécanica Osea
Nutrición
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
topic Mandibula
Biomécanica Osea
Nutrición
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
description This study describes the effects of feeding growing rats with a diet containing inadequate and incomplete proteins on both the morphological and the biomechanical properties of the mandible. Female rats aged 30 d were fed freely with one of two diets, control (CD, 301 Cal/100g) and experimental (ED, 359 Cal/100g). CD was a standard laboratory diet, while ED was a synthetic diet containing cornflower supplemented with vitamins and minerals. Both diets had the same physical characteristics. Control (C) and experimental (E) animals were divided into 4 groups of 10 animals each. C40 and E40 rats were fed CD and ED, respectively, for 40 d; C105 were fed the CD for 105 d; and E105 were fed the ED for 40 d and then the CD for the remainder of the experimental period (65 d). Mandibular growth was estimated directly on excised and cleaned bones by taking measurements between anatomical points. Mechanical properties of the right hemimandible were estimated by using a 3-point bending test to estimate the structural properties of the bone. Geometric properties of both the entire bone and the cross-section were determined. Bone material properties were calculated from structural and geometric properties. The left hemimandibles were ashed and the ash weight obtained. Rats fed the ED failed to achieve normal body weight gain. Complete catch-up was observed at the end of nutritional rehabilitation. Mandibular weight and length were negatively affected by the ED, as were the cross-sectional area, the mineralized cortical area, and the cross-sectional moment of inertia. All of these parameters showed incomplete catch-up. The structural bone mechanical properties indicative of strength and stiffness were negatively affected. Intrinsic material properties, as assessed by the modulus of elasticity and maximal elastic stress, were within normal values. In summary, the experimental bone was weaker than the control and structurally incompetent. The bone considered was smaller than the control bone, showing a significant reduction in the cross-sectional area and the moment of inertia. However, material properties as well as the ash fraction and degree of mineralization were similar in E and C bones. Therefore, the E bone was weaker than the C bone because of its smaller bone mass, which appears to have been negatively influenced by the ED in relation to its effects on overall body mass
publishDate 2013
dc.date.none.fl_str_mv 2013-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/1932
Bozzini, Clarisa; Champin, Graciela Monica; Bozzini, Carlos Eduardo Jose; Alippi, Rosa Maria; Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics; Sociedad Argentina de Investigación Odontológica; Acta Odontológica Latinoamericana; 26; 1; 5-2013; 43-53
0326-4815
1852-4834
url http://hdl.handle.net/11336/1932
identifier_str_mv Bozzini, Clarisa; Champin, Graciela Monica; Bozzini, Carlos Eduardo Jose; Alippi, Rosa Maria; Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics; Sociedad Argentina de Investigación Odontológica; Acta Odontológica Latinoamericana; 26; 1; 5-2013; 43-53
0326-4815
1852-4834
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/reference es info:eu-repo/semantics/reference/pmid/24294823
info:eu-repo/semantics/altIdentifier/url/http://www.scielo.org.ar/pdf/aol/v26n1/v26n1a07.pdf
info:eu-repo/semantics/altIdentifier/url/http://www.actaodontologicalat.com/archivo/v26n1/07.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedad Argentina de Investigación Odontológica
publisher.none.fl_str_mv Sociedad Argentina de Investigación Odontológica
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1799196156931080192
spelling Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanicsBozzini, ClarisaChampin, Graciela MonicaBozzini, Carlos Eduardo JoseAlippi, Rosa MariaMandibulaBiomécanica OseaNutriciónhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3This study describes the effects of feeding growing rats with a diet containing inadequate and incomplete proteins on both the morphological and the biomechanical properties of the mandible. Female rats aged 30 d were fed freely with one of two diets, control (CD, 301 Cal/100g) and experimental (ED, 359 Cal/100g). CD was a standard laboratory diet, while ED was a synthetic diet containing cornflower supplemented with vitamins and minerals. Both diets had the same physical characteristics. Control (C) and experimental (E) animals were divided into 4 groups of 10 animals each. C40 and E40 rats were fed CD and ED, respectively, for 40 d; C105 were fed the CD for 105 d; and E105 were fed the ED for 40 d and then the CD for the remainder of the experimental period (65 d). Mandibular growth was estimated directly on excised and cleaned bones by taking measurements between anatomical points. Mechanical properties of the right hemimandible were estimated by using a 3-point bending test to estimate the structural properties of the bone. Geometric properties of both the entire bone and the cross-section were determined. Bone material properties were calculated from structural and geometric properties. The left hemimandibles were ashed and the ash weight obtained. Rats fed the ED failed to achieve normal body weight gain. Complete catch-up was observed at the end of nutritional rehabilitation. Mandibular weight and length were negatively affected by the ED, as were the cross-sectional area, the mineralized cortical area, and the cross-sectional moment of inertia. All of these parameters showed incomplete catch-up. The structural bone mechanical properties indicative of strength and stiffness were negatively affected. Intrinsic material properties, as assessed by the modulus of elasticity and maximal elastic stress, were within normal values. In summary, the experimental bone was weaker than the control and structurally incompetent. The bone considered was smaller than the control bone, showing a significant reduction in the cross-sectional area and the moment of inertia. However, material properties as well as the ash fraction and degree of mineralization were similar in E and C bones. Therefore, the E bone was weaker than the C bone because of its smaller bone mass, which appears to have been negatively influenced by the ED in relation to its effects on overall body massFil: Bozzini, Clarisa. Universidad de Buenos Aires. Facultad de Odontología. Cátedra de Fisiología; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina;Fil: Champin, Graciela Monica. Universidad de Buenos Aires. Facultad de Odontología. Cátedra de Fisiología; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina;Fil: Bozzini, Carlos Eduardo Jose. Universidad de Buenos Aires. Facultad de Odontología. Cátedra de Fisiología; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina;Fil: Alippi, Rosa Maria. Universidad de Buenos Aires. Facultad de Odontología. Cátedra de Fisiología; Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina;Sociedad Argentina de Investigación Odontológica2013-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/1932Bozzini, Clarisa; Champin, Graciela Monica; Bozzini, Carlos Eduardo Jose; Alippi, Rosa Maria; Growth inhibition in rats fed inadequate and incomplete proteins: repercussion on mandibular biomechanics; Sociedad Argentina de Investigación Odontológica; Acta Odontológica Latinoamericana; 26; 1; 5-2013; 43-530326-48151852-4834enginfo:eu-repo/semantics/reference es info:eu-repo/semantics/reference/pmid/24294823info:eu-repo/semantics/altIdentifier/url/http://www.scielo.org.ar/pdf/aol/v26n1/v26n1a07.pdfinfo:eu-repo/semantics/altIdentifier/url/http://www.actaodontologicalat.com/archivo/v26n1/07.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T14:16:51Zoai:ri.conicet.gov.ar:11336/1932instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 14:16:51.331CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
score 15,81155

Similares en LA Referencia