Effect of Lactobacillus reuteri on the prevention of hypercholesterolemia in mice
Administration of Lactobacillus reuteri CRL 1098 (104 cells/d) to mice for 7 d before inducing hypercholesterolemia (by feeding mice with a fat-enriched diet for the subsequent 7 d) was evaluated. At this low dose, L. reuteri was effective in preventing hypercholesterolemia in mice, producing a 17%...
| Autores: | , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2000 |
| País: | Argentina |
| Recursos: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositório: | CONICET Digital (CONICET) |
| Idioma: | inglês |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/51604 |
| Acesso em linha: | http://hdl.handle.net/11336/51604 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Hypocholesterolemia Lactobacillus Reuteri Probiotic https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| Resumo: | Administration of Lactobacillus reuteri CRL 1098 (104 cells/d) to mice for 7 d before inducing hypercholesterolemia (by feeding mice with a fat-enriched diet for the subsequent 7 d) was evaluated. At this low dose, L. reuteri was effective in preventing hypercholesterolemia in mice, producing a 17% increase in the ratio of high-density lipoprotein to low-density lipoprotein. Total cholesterol and triglycerides decreased by 22 and 33%, respectively, in the group that was not fed the lactobacilli. The hypocholesterolemic effect produced by L. reuteri CRL 1098 might be considered as indirect evidence of the permanency of the lactobacilli in the gut. |
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