Effect of Lactobacillus reuteri on the prevention of hypercholesterolemia in mice

Administration of Lactobacillus reuteri CRL 1098 (104 cells/d) to mice for 7 d before inducing hypercholesterolemia (by feeding mice with a fat-enriched diet for the subsequent 7 d) was evaluated. At this low dose, L. reuteri was effective in preventing hypercholesterolemia in mice, producing a 17%...

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Detalles Bibliográficos
Autores: Taranto, Maria Pia, Medici, Marta Graciela, Perdigon, Gabriela del Valle, Pesce de Ruiz Holgado, Aida Argentina, Font, Graciela Maria
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2000
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/51604
Acceso en línea:http://hdl.handle.net/11336/51604
Access Level:acceso abierto
Palabra clave:Hypocholesterolemia
Lactobacillus Reuteri
Probiotic
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
Descripción
Sumario:Administration of Lactobacillus reuteri CRL 1098 (104 cells/d) to mice for 7 d before inducing hypercholesterolemia (by feeding mice with a fat-enriched diet for the subsequent 7 d) was evaluated. At this low dose, L. reuteri was effective in preventing hypercholesterolemia in mice, producing a 17% increase in the ratio of high-density lipoprotein to low-density lipoprotein. Total cholesterol and triglycerides decreased by 22 and 33%, respectively, in the group that was not fed the lactobacilli. The hypocholesterolemic effect produced by L. reuteri CRL 1098 might be considered as indirect evidence of the permanency of the lactobacilli in the gut.