Gelatin films dendronized selectively on one side. Enhancing antimicrobial properties and water repellence

To develop a material with potential biomedical applications, novelgelatin films were prepared by cold-casting method using cerium(III) and genipinsolution as cross-linking agents, and surface modified with dendritic molecules. Thestructure and properties of the synthesized gelatin films were invest...

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Detalles Bibliográficos
Autores: García Schejtman, Sergio Davi, Toselli, Ricard, Strumia, Miriam Cristina, Martinelli, Marisa
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/12657
Acceso en línea:http://hdl.handle.net/11336/12657
Access Level:acceso abierto
Palabra clave:Biomaterials
Gelatin Films
Dendronization
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:To develop a material with potential biomedical applications, novelgelatin films were prepared by cold-casting method using cerium(III) and genipinsolution as cross-linking agents, and surface modified with dendritic molecules. Thestructure and properties of the synthesized gelatin films were investigated by ATRFTIR,mechanical tests, swelling behavior and water vapor permeability (WVP).The results showed that cross-linking could improve the mechanical and microbiologicalproperties and lower the hydrophilic property of gelatin films. According toATR-FTIR analysis, it can be concluded that the dendronization took place on onlyone of the faces of the films. The results have shown that the experimentalmethodology performed allows one-surface modification, so a novel biomaterialwas obtained in the form of a film with good properties and dendritic structure inone face (hydrophobic and hydrophilic faces), rendering a multivalent structureuseful in biomedicine development.