Chelation Therapies: A Chemical and Biochemical Perspective

Chelation therapy occupies a central place in modern medicine and pharmacology, beacuse continuous studies with laboratory animals and extensive clinical experience demonstrate that accute or chronic intoxications with a variety of metals can be considerable improved by administration of a suitable...

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Detalles Bibliográficos
Autor: Baran, Enrique José
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/103522
Acceso en línea:http://hdl.handle.net/11336/103522
Access Level:acceso abierto
Palabra clave:TOXIC METALS
CHELATING AGENTS
CHEMICAL CHARACTERISTICS
BIOLOGICAL EFFECTS
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
Descripción
Sumario:Chelation therapy occupies a central place in modern medicine and pharmacology, beacuse continuous studies with laboratory animals and extensive clinical experience demonstrate that accute or chronic intoxications with a variety of metals can be considerable improved by administration of a suitable chelating agent. In this review the chemical characteristics, properties and uses of the most common chelating agents as well as those of some new and very promising agents of this type, are discussed. In the second part of the review the biological and biochemical impact of these agents, as well as their use for the treatment of some selected diseases and disorders, are also analyzed and discussed in detail.