Forms of Iron Binding in the Cells and the Chemical Features of Chelation Therapy

Iron is essential for human life, however it can be toxic through Fe ability to generate oxygen-derived radicals. This work reviews the main features of Fe binding in the cell and its association to these processes. The chemical nature of the Fe extracted by chelation therapy in pathophysiological s...

Full description

Bibliographic Details
Authors: Puntarulo, Susana Ángela, Galleano, Mónica Liliana
Format: article
Status:Published version
Publication Date:2009
Country:Argentina
Institution:Consejo Nacional de Investigaciones Científicas y Técnicas
Repository:CONICET Digital (CONICET)
Language:English
OAI Identifier:oai:ri.conicet.gov.ar:11336/102920
Online Access:http://hdl.handle.net/11336/102920
Access Level:Open access
Keyword:IRON
IRON CHELATION
PHYSICAL CHEMICAL PROPERTIES
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
Description
Summary:Iron is essential for human life, however it can be toxic through Fe ability to generate oxygen-derived radicals. This work reviews the main features of Fe binding in the cell and its association to these processes. The chemical nature of the Fe extracted by chelation therapy in pathophysiological situations is also analyzed.