Human outbreak of St. Louis encephalitis detected in Argentina, 2005

Background: An outbreak of flavivirus encephalitis occurred in 2005 in Córdoba province, Argentina. Objectives: To characterize the epidemiologic and clinical features of that outbreak and provide the serologic results that identified St. Louis encephalitis virus (SLEV) as the etiologic agent. Study...

Descripción completa

Detalles Bibliográficos
Autores: Spinsanti, Lorena Ivana, Diaz, Luis Adrian, Glatstein, Nora Viviana, Arselán, Sergio, Morales, María A., Farias, Adrian Alejandro, Fabbri, Cintia, Aguilar, Juán J., Ré, Viviana Elizabeth, Frías, María, Almiron, Walter Ricardo, Hunsperger, Elizabeth, Siirin, Marina, Da Rosa, Amelia Travassos, Tesh, Robert B., Enría, Delia, Contigiani de Minio, Marta Silvia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/59028
Acceso en línea:http://hdl.handle.net/11336/59028
Access Level:acceso abierto
Palabra clave:Argentina
Encephalitis Outbreak
Slev Antibodies
St. Louis Encephalitis Virus
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
Descripción
Sumario:Background: An outbreak of flavivirus encephalitis occurred in 2005 in Córdoba province, Argentina. Objectives: To characterize the epidemiologic and clinical features of that outbreak and provide the serologic results that identified St. Louis encephalitis virus (SLEV) as the etiologic agent. Study design: From January to May 2005, patients with symptoms of encephalitis, meningitis, or fever with severe headache were evaluated and an etiologic diagnosis achieved by detection of flavivirus-specific antibody sera and cerebrospinal fluid. Results: The epidemic curve of 47 cases showed an explosive outbreak starting in January 2005 with one peak in mid-February and a second peak in mid-March; the epidemic ended in May. Cases occurred predominantly among persons 60 years and older. Nine deaths were reported. SLEV antibodies, when detected in 47 patients studied, had a pattern characteristic of a primary SLEV infection. Conclusions: Even though isolated cases of St. Louis encephalitis have been reported in Argentina, this is the first description of a large SLEV encephalitis outbreak in Argentina.

Similares en LA Referencia