Seroprevalence of St. Louis Encephalitis Virus and West Nile Virus (Flavivirus, Flaviviridae) in Horses, Uruguay

St. Louis encephalitis virus (SLEV) and West Nile virus (WNV) belong to the Japanese encephalitis antigenic complex (Flavivirus genus, Flaviviridae family). They show antigenic close relationships and share many similarities in their ecology. Both are responsible for serious human diseases. The aim...

ver descrição completa

Detalhes bibliográficos
Autores: Burgueño, Analía, Spinsanti, Lorena Ivana, Diaz, Luis Adrian, Rivarola, María Elisa, Arbiza, Juan, Contigiani de Minio, Marta Silvia, Delfraro, Adriana
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2013
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositório:CONICET Digital (CONICET)
Idioma:inglês
OAI Identifier:oai:ri.conicet.gov.ar:11336/25269
Acesso em linha:http://hdl.handle.net/11336/25269
Access Level:Acceso aberto
Palavra-chave:ST. LOUIS ENCEPHALITIS VIRUS
WEST NILE VIRUS
HORSES
URUGUAY
NEUTRALIZING ANTIBODIES
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
Descrição
Resumo:St. Louis encephalitis virus (SLEV) and West Nile virus (WNV) belong to the Japanese encephalitis antigenic complex (Flavivirus genus, Flaviviridae family). They show antigenic close relationships and share many similarities in their ecology. Both are responsible for serious human diseases. The aim of this study was to investigate the presence of neutralizing antibodies to these viruses in horses from Uruguay. To do this, 425 horse sera were collected in 2007 and analyzed by plaque reduction neutralization tests. As a result, 205 sera (48.2%) were found positive for SLEV, with titers ranging between 10 and 80. Two sera remained inconclusive, since they showed low titers to WNV and SLEV (10 and 20), not allowing us to demonstrate activity of WNV in our territory. This is the first report of circulation of SLEV in horses in Uruguay.